Roles of Interleukin-6-mediated immunometabolic reprogramming in COVID-19 and other viral infection-associated diseases

YS Li, HC Ren, JH Cao - International Immunopharmacology, 2022 - Elsevier
Abstract Interleukin-6 (IL-6) is a highly pleiotropic glycoprotein factor that can modulate
innate and adaptive immunity as well as various aspects of metabolism, including glycolysis …

[HTML][HTML] Tumor necrosis factor-alpha inhibitors and cardiovascular risk in rheumatoid arthritis: a systematic review

S Nair, SS Kahlon, R Sikandar, A Peddemul… - Cureus, 2022 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is an autoimmune disease that, if untreated or poorly controlled,
can cause significant morbidity in terms of loss of physical function and higher mortality due …

[HTML][HTML] A novel biomarker of interleukin 6 activity and clinical and cognitive outcomes in depression

ÉM Foley, C Slaney, NA Donnelly, M Kaser… - …, 2024 - Elsevier
Background Inflammatory cytokines like interleukin-6 (IL-6) are implicated in depression, but
most studies have hitherto focused on circulating levels of IL-6 rather than its activity. IL-6 …

[HTML][HTML] Inhibitory effects of Ganoderma lucidum spore oil on rheumatoid arthritis in a collagen-induced arthritis mouse model

Y Heo, M Kim, GGD Suminda, Y Min, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Holistic healthcare practitioners have now started to focus on specific traditional medicinal
mushrooms to treat rheumatoid arthritis (RA). Ganoderma lucidum (GL) is one of the oldest …

Juvenile idiopathic arthritis

M Sudhakar, S Kumar - Indian Journal of Pediatrics, 2024 - Springer
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. The
International League of Associations for Rheumatology (ILAR) has defined JIA as “arthritis of …

Autoimmunity, cancer and COVID-19 abnormally activate wound healing pathways: Critical role of inflammation

P Gál, J Brábek, M Holub, M Jakubek, A Šedo… - Histochemistry and Cell …, 2022 - Springer
Recent evidence indicates that targeting IL-6 provides broad therapeutic approaches to
several diseases. In patients with cancer, autoimmune diseases, severe respiratory …

Comparative Chemical Analysis of Eight Punica granatum L. Peel Cultivars and Their Antioxidant and Anti-Inflammatory Activities

V Parisi, V Santoro, G Donadio, ML Bellone, G Diretto… - Antioxidants, 2022 - mdpi.com
A comparative quali-quantitative study of the peel extracts of eight Punica granatum cultivars
obtained from underexploited areas of South Italy was carried out in order to valorize them …

HSP90 exacerbates bone destruction in rheumatoid arthritis by activating TRAF6/NFATc1 signaling

Q Wang, X Kong, W Guo, L Liu, Y Tian, X Tao, N Lin… - Inflammation, 2024 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease characterized by a notably high
disability rate, primarily attributed to cartilage and bone degradation. The involvement of …

[HTML][HTML] Перспективы ингибиции интерлейкина-6 при ревматоидном артрите: олокизумаб (новые моноклональные антитела к ИЛ-6)

ЕЛ Насонов, Е Файст - Научно-практическая ревматология, 2022 - cyberleninka.ru
Ревматоидный артрит (РА)-хроническое иммуновоспалительное ревматическое
заболевание (ИВРЗ), проявляющееся прогрессирующей деструкцией суставов …

Panlongqi tablet suppresses adjuvant-induced rheumatoid arthritis by inhibiting the inflammatory reponse in vivo and in vitro

X Niu, Y Yang, J Yu, H Song, J Yu, Q Huang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Panlongqi Tablet is prepared with the ancestral
secret recipe provided by Mr. Wang Jiacheng, a famous specialist in orthopedics and …