The classical and non-classical axes of renin-angiotensin system in Parkinson disease: the bright and dark side of the moon

HM Al-Kuraishy, SM Al-Hamash, MS Jabir… - Ageing Research …, 2024 - Elsevier
Parkinson disease (PD) is a common brain neurodegenerative disease due to progressive
degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNpc). Of …

[HTML][HTML] Pentoxifylline and berberine mitigate diclofenac-induced acute nephrotoxicity in male rats via modulation of inflammation and oxidative stress

M Alorabi, S Cavalu, HM Al-Kuraishy… - Biomedicine & …, 2022 - Elsevier
Nephrotoxicity (NT) is a renal-specific situation caused by different toxins and drugs like non-
steroidal anti-inflammatory drugs (NSAIDs). NSAIDs like diclofenac (DCF) lead to glomerular …

Mitochondrial targeted antioxidant SKQ1 ameliorates acute kidney injury by inhibiting ferroptosis

J Song, J Sheng, J Lei, W Gan… - Oxidative Medicine and …, 2022 - Wiley Online Library
Emerging evidence suggests that ferroptosis is highly correlated with the pathogenesis of
acute kidney injury (AKI). Ferroptosis, an iron‐dependent form of cell death, is manifested by …

[HTML][HTML] New insight into the effect of lycopene on the oxidative stress in acute kidney injury

HA Rasheed, MS Al-Naimi, NR Hussien… - … Journal of Critical …, 2020 - journals.lww.com
Objective: To evaluate the nephroprotective effect of lycopene (LPN) in acute kidney injury
(AKI) regarding the oxidative stress (OS). Materials and Methods: Thirty Sprague Dawley …

Insights into the role of PHLPP2/Akt/GSK3β/Fyn kinase/Nrf2 trajectory in the reno-protective effect of rosuvastatin against colistin-induced acute kidney injury in rats

MS Shafik, DM El-Tanbouly, A Bishr… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives Oxidative stress-mediated colistin's nephrotoxicity is associated with the
diminished activity of nuclear factor erythroid 2-related factor 2 (Nrf2) that is primarily …

[HTML][HTML] Possible role of statins on the inflammatory biomarkers in patients with periodontal disease: a cross-sectional study

SS Kadhim, SA Al-Windy, MS Al-Nami… - Dental …, 2019 - journals.lww.com
Materials and Methods: This cross-sectional study involved 74 patients with PD and/or
dyslipidemia divided into Group A: 34 patients with PD (nonstatins users); Group B: 40 …

Hyaluronidase inhibitor sHA2. 75 alleviates ischemia-reperfusion-induced acute kidney injury

Y Zhang, H Zhao, J Zhang - Cell Cycle, 2024 - Taylor & Francis
Hyaluronidases (HAases) are enzymes that degrade hyaluronic acid (HA) in the animal
kingdom. The HAases-HA system is crucial for HA homeostasis and plays a significant role …

[HTML][HTML] Rosuvastatin induces renal HO-1 activity and expression levels as a main protective mechanism against STZ-induced diabetic nephropathy

GH Heeba, MAM Ali, AAK El-Sheikh - Medicina, 2022 - mdpi.com
Background and Objectives: Nephroprotective effect of statins is still controversial. The aim
of this study was to investigate the possible hemin-like nephroprotective effect of …

[PDF][PDF] Intercellular adhesive molecule 1 (ICAM-1) and acute ischaemic stroke: role of statins

HF Al-Rubiay, HM Al-Kuraishy, AI Al-Gareeb - J Pak Med Assoc, 2021 - researchgate.net
Objectives: To demonstrate the differential effect of atorvastatin and rosuvastatin on the
Intercellular adhesive molecule 1 (ICAM-1) in acute ischaemic stroke (AIS) patients …

Effects of Quercetin and Coenzyme Q10 on gentamicin-induced nephrotoxicity in rats

N Pınar, Y Karataş, YK Dağlıoğlu… - Cukurova Medical …, 2020 - dergipark.org.tr
Purpose: We investigated the effects of Quercetin and Coenzyme Q10 antioxidant, on
gentamicin-induced renal failure in rats. Amaç: Gentamisinle böbrek yetmezliği oluşturulan …