[HTML][HTML] Current achievements and applications of transcriptomics in personalized cancer medicine

S Supplitt, P Karpinski, M Sasiadek… - International Journal of …, 2021 - mdpi.com
Over the last decades, transcriptome profiling emerged as one of the most powerful
approaches in oncology, providing prognostic and predictive utility for cancer management …

[HTML][HTML] Circulating RNAs in prostate cancer patients

V Mugoni, Y Ciani, C Nardella, F Demichelis - Cancer letters, 2022 - Elsevier
Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …

Exosome detection via the ultrafast-isolation system: EXODUS

Y Chen, Q Zhu, L Cheng, Y Wang, M Li, Q Yang, L Hu… - Nature …, 2021 - nature.com
Exosomes have shown great potential in disease diagnostics and therapeutics. However,
current isolation approaches are burdensome and suffer from low speed, yield and purity …

A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER)

J Zhang, C Chen, R Becker, J Rufo, S Yang, J Mai… - Science …, 2022 - science.org
High-precision isolation of small extracellular vesicles (sEVs) from biofluids is essential
toward developing next-generation liquid biopsies and regenerative therapies. However …

[HTML][HTML] Exosomes in prostate cancer diagnosis, prognosis and therapy

T Lorenc, K Klimczyk, I Michalczewska… - International Journal of …, 2020 - mdpi.com
Prostate cancer (PCa) is the second most common cause of cancer-related mortality among
men in the developed world. Conventional anti-PCa therapies are not effective for patients …

[HTML][HTML] Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

[HTML][HTML] Advances in the molecular landscape of lung cancer brain metastasis

VGP Souza, RP de Araújo, MR Santesso, AL Seneda… - Cancers, 2023 - mdpi.com
Simple Summary Patients with lung cancer have high rates of brain metastasis (BM).
Despite available therapies, patient prognosis is poor. Studies have shown genetic …

Genomic testing in patients with metastatic castration-resistant prostate cancer: a pragmatic guide for clinicians

AS Merseburger, N Waldron, MJ Ribal, A Heidenreich… - European Urology, 2021 - Elsevier
Context Genomic testing is becoming increasingly important in patients with advanced
prostate cancer (PC) and is being incorporated in clinical practice to guide treatment …

[HTML][HTML] Proteomic analyses of fibroblast-and serum-derived exosomes identify QSOX1 as a marker for non-invasive detection of colorectal cancer

N Ganig, F Baenke, ML Thepkaysone, K Lin, VS Rao… - Cancers, 2021 - mdpi.com
Simple Summary Early diagnosis of colorectal cancer (CRC) is crucial to improve patient
outcomes. The tumour microenvironment immediately adapts to malignant transformations …

[HTML][HTML] Sensor-integrated microfluidic approaches for liquid biopsies applications in early detection of cancer

J Sierra, J Marrugo-Ramirez, R Rodriguez-Trujillo… - Sensors, 2020 - mdpi.com
Cancer represents one of the conditions with the most causes of death worldwide. Common
methods for its diagnosis are based on tissue biopsies—the extraction of tissue from the …