Atherosclerosis is the leading cause of death worldwide and leukocyte recruitment is a key
element of this phenomenon, thus allowing immune cells to enter the arterial wall. There, in …

Despite all the advances of modern medicine, atherosclerosis continues to be one of the
most important medical and social problems. Atherosclerosis is the cause of several …

Membrane cholesterol is essential for cell membrane properties, just as serum cholesterol is
important for the transport of molecules between organs. This review focuses on cholesterol …

Statins play a major role in reducing circulating cholesterol levels and are widely used to
prevent coronary artery disease. Although they are recently confirmed to up-regulate …

Atherosclerosis research typically focuses on the evolution of intermediate or advanced
atherosclerotic lesions rather than on prelesional stages of atherogenesis. Yet these early …

Atherosclerosis manifests by the thickening of artery walls and their narrowed channels
through the accumulation of plaque. It is one of the most important indicators of …

Macrophages in atherosclerotic patients are notably plastic and heterogeneous. Single-cell
RNA sequencing (Sc RNA-seq) can provide information about all the RNAs in individual …

Apolipoproteins, the protein component of lipoproteins, play an important role in lipid
transport, lipoprotein assembly, and receptor recognition. Apolipoproteins are glycosylated …

Atherosclerosis is the major cause of cardiovascular-disease-related death worldwide,
resulting from the subendothelial accumulation of lipoprotein-derived cholesterol, ultimately …

Atherosclerosis is a chronic inflammatory disease [1, 2] which manifests in the pathological
thickening of the walls of large arteries, and is related to lipid depositions. Lipids, including …