The Type VI secretion system: a versatile bacterial weapon

S Coulthurst - Microbiology, 2019 - microbiologyresearch.org
The Type VI secretion system (T6SS) is a protein nanomachine that is widespread in Gram-
negative bacteria and is used to translocate effector proteins directly into neighbouring cells …

Genomic and Metabolic Characteristics of the Pathogenicity in Pseudomonas aeruginosa

T De Sousa, M Hébraud, MLNE Dapkevicius… - International journal of …, 2021 - mdpi.com
In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Aim, load, fire: the type VI secretion system, a bacterial nanoweapon

FR Cianfanelli, L Monlezun, SJ Coulthurst - Trends in microbiology, 2016 - cell.com
Bacteria utilise specialised protein secretion systems to interact with host organisms,
competitor bacteria, and the environment. The Type VI secretion system (T6SS) is a versatile …

Identification of protein secretion systems in bacterial genomes

SS Abby, J Cury, J Guglielmini, B Néron, M Touchon… - Scientific reports, 2016 - nature.com
Bacteria with two cell membranes (diderms) have evolved complex systems for protein
secretion. These systems were extensively studied in some model bacteria, but the …

Activity, delivery, and diversity of Type VI secretion effectors

D Jurėnas, L Journet - Molecular Microbiology, 2021 - Wiley Online Library
The bacterial type VI secretion system (T6SS) system is a contractile secretion apparatus
that delivers proteins to neighboring bacterial or eukaryotic cells. Antibacterial effectors are …

The Pseudomonas putida T6SS is a plant warden against phytopathogens

P Bernal, LP Allsopp, A Filloux, MA Llamas - The ISME journal, 2017 - academic.oup.com
Bacterial type VI secretion systems (T6SSs) are molecular weapons designed to deliver
toxic effectors into prey cells. These nanomachines have an important role in inter-bacterial …

Type VI secretion systems in plant‐associated bacteria

P Bernal, MA Llamas, A Filloux - Environmental microbiology, 2018 - Wiley Online Library
The type VI secretion system (T6SS) is a bacterial nanomachine used to inject effectors into
prokaryotic or eukaryotic cells and is thus involved in both host manipulation and …

A type VI secretion-related pathway in Bacteroidetes mediates interbacterial antagonism

AB Russell, AG Wexler, BN Harding, JC Whitney… - Cell host & …, 2014 - cell.com
Bacteroidetes are a phylum of Gram-negative bacteria abundant in mammalian-associated
polymicrobial communities, where they impact digestion, immunity, and resistance to …

An overview of anti-eukaryotic T6SS effectors

J Monjarás Feria, MA Valvano - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
The type VI secretion system (T6SS) is a transmembrane multiprotein nanomachine
employed by many Gram-negative bacterial species to translocate, in a contact-dependent …

Agrobacterium tumefaciens deploys a superfamily of type VI secretion DNase effectors as weapons for interbacterial competition in planta

LS Ma, A Hachani, JS Lin, A Filloux, EM Lai - Cell host & microbe, 2014 - cell.com
The type VI secretion system (T6SS) is a widespread molecular weapon deployed by many
Proteobacteria to target effectors/toxins into both eukaryotic and prokaryotic cells. We report …