The respiratory tract is one of the most accessible ones to exogenous nanoparticles, yet
drug delivery by their means to it is made extraordinarily challenging because of the plexus …

Mesenchymal stromal cells (MSCs) as a kind of pluripotent adult stem cell have shown great
therapeutic potential in relation to many diseases in anti-inflammation and regeneration. The …

Pulmonary fibrosis induced by silica dust is an irreversible, chronic, and fibroproliferative
lung disease with no effective treatment at present. BMSCs-derived exosomes (BMSCs-Exo) …

Mesenchymal stem cells (MSCs) have shown promising therapeutic effects in cell-based
therapies and regenerative medicine. Efficient tracking of MSCs is an urgent clinical need …

In the last decade, nanocarriers have been widely used to target specific organs and
disorders of any kind. Nonetheless, the commercialization of nanocarriers for many …

Nanoparticles play a vital role in bone tissue repair engineering, especially iron oxide
nanoparticles (IONPs), which have magnetic properties, semiconductor properties, and …

Most chronic diseases involving inflammation have a fibrotic component that involves
remodeling and excess accumulation of extracellular matrix components. Left unchecked …

Background Autophagy is a catabolic process that recycles damaged organelles and acts as
a pro-survival mechanism, but little is known about autophagy dysfunction and epigenetic …

AIM To reveal whether and how Yes-associated protein (YAP) promotes the occurrence of
subretinal fibrosis in age-related macular degeneration (AMD). METHODS Cobalt chloride …

Stem cell-based therapies have been shown potential in regenerative medicine. In these
cells, mesenchymal stem cells (MSCs) have the ability of self-renewal and being …