Predictors of morbidity and mortality in contemporary Fontan patients: results from a multicenter study including cardiopulmonary exercise testing in 321 patients

GP Diller, A Giardini, K Dimopoulos… - European heart …, 2010 - academic.oup.com
Aims Previous studies have established an association between exercise intolerance and
increased morbidity and mortality in congenital heart disease patients. We aimed to clarify if …

Comprehensive use of cardiopulmonary exercise testing identifies adults with congenital heart disease at increased mortality risk in the medium term

R Inuzuka, GP Diller, F Borgia, L Benson, ELW Tay… - Circulation, 2012 - Am Heart Assoc
Background—Parameters of cardiopulmonary exercise testing were recently identified as
strong predictors of mortality in adults with congenital heart disease. We hypothesized that …

A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation

SM Paridon, PD Mitchell, SD Colan, RV Williams… - Journal of the American …, 2008 - jacc.org
Objectives: The aim of this study was to describe exercise performance during the first 2
decades of life in Fontan survivors by a cross-sectional study and to identify factors that …

Abnormal ventilatory response to exercise in adults with congenital heart disease relates to cyanosis and predicts survival

K Dimopoulos, DO Okonko, GP Diller, CS Broberg… - Circulation, 2006 - Am Heart Assoc
Background—Limited data exist with which to stratify risk in adult congenital heart disease
(ACHD). An increased ventilatory response to exercise, expressed as ventilation per unit of …

Physical activity levels in children and adolescents are reduced after the Fontan procedure, independent of exercise capacity, and are associated with lower perceived …

BW McCrindle, RV Williams, S Mital, BJ Clark… - Archives of disease in …, 2007 - adc.bmj.com
Objectives: To determine physical activity levels in paediatric patients who underwent the
Fontan procedure, and their relationship to functional status and exercise capacity. Study …

Impact of cardiac rehabilitation on the exercise function of children with serious congenital heart disease

J Rhodes, TJ Curran, L Camil, N Rabideau… - …, 2005 - publications.aap.org
Objectives. The exercise capacity of children with congenital heart disease (CHD) is often
depressed. This depression is thought to be attributable to (1) residual hemodynamic …

The long-term management of children and adults with a Fontan circulation: a systematic review and survey of current practice in Australia and New Zealand

GK Gnanappa, DS Celermajer, GF Sholler, T Gentles… - Pediatric …, 2017 - Springer
Although long-term survival is now the norm, Fontan patients face significant morbidity and
premature mortality. Wide variation exists in long-term Fontan management. With an aim of …

Exercise limitation in patients with Fontan circulation: a review

T Takken, MHP Tacken, AC Blank… - Journal of …, 2007 - journals.lww.com
The aim of the current literature study was to perform a literature review of the factors
contributing to exercise limitation and physiological response to exercise in patients with …

Multicenter study of pectus excavatum, final report: complications, static/exercise pulmonary function, and anatomic outcomes

RE Kelly Jr, RB Mellins, RC Shamberger… - Journal of the American …, 2013 - Elsevier
Background A multicenter study of pectus excavatum was described previously. This report
presents our final results. Study Design Patients treated surgically at 11 centers were …

Exercise testing and training in children with congenital heart disease

J Rhodes, A Ubeda Tikkanen, KJ Jenkins - Circulation, 2010 - Am Heart Assoc
The primary function of the cardiopulmonary system is to provide blood flow (and oxygen) in
quantities sufficient to support the metabolic needs of the body. The capacity of the …