Mass spectrometry-based determination of lipids and small molecules composing adipose tissue with a focus on brown adipose tissue

K Miniewska, J Godzien, P Mojsak… - … of Pharmaceutical and …, 2020 - Elsevier
Adipose tissue has been the subject of research for a very long time. Many studies perform a
comprehensive analysis of different types of adipose tissue with an emphasis on brown …

Escherichia coli possessing the dihydroxyacetone phosphate shunt utilize 5′-deoxynucleosides for growth

KA Huening, JT Groves, JA Wildenthal… - Microbiology …, 2024 - Am Soc Microbiol
All organisms utilize S-adenosyl-l-methionine (SAM) as a key co-substrate for the
methylation of biological molecules, the synthesis of polyamines, and radical SAM reactions …

Determination of amino acids in colon cancer cells by using UHPLC-MS/MS and [U-13C5]-glutamine as the isotope tracer

X Li, CC Wong, Z Tang, J Wu, S Li, Y Qian, J Xu… - Talanta, 2017 - Elsevier
Rapid and simple quantitative analysis of intracellular metabolites is a critical tool for
monitoring the alteration of biologically significant metabolites in cell lines or in vivo. We …

[HTML][HTML] Gut microbiota and metabolic biomarkers in metabolic dysfunction–associated steatotic liver disease

Q Long, F Luo, B Li, Z Li, Z Guo, Z Chen… - Hepatology …, 2024 - journals.lww.com
Metabolic dysfunction–associated steatotic liver disease (MASLD), a replacement of the
nomenclature employed for NAFLD, is the most prevalent chronic liver disease worldwide …

Targeted metabolomics for the quantitative measurement of 9 gut microbiota–host co-metabolites in rat serum, urine and feces by liquid chromatography–tandem …

Y Zeng, Y Lin, L Li, Y Li, X Zhang, M Wang… - … of Chromatography B, 2019 - Elsevier
Gut microbiota–host co-metabolites play an essential role in maintaining homeostasis, and
their concentration changes are closely related to a variety of diseases. Developing a …

[HTML][HTML] Translational Potential of Metabolomics on Animal Models of Inflammatory Bowel Disease—A Systematic Critical Review

LA Knudsen, R Desdorf, S Möller, SB Sørensen… - International Journal of …, 2020 - mdpi.com
In the development of inflammatory bowel disease (IBD), the gut microbiota has been
established as a key factor. Recently, metabolomics has become important for …

Targeted metabolomics analysis of aromatic amino acids and their gut microbiota–host cometabolites in rat serum and urine by liquid chromatography coupled with …

Y Zeng, L Luo, W Hou, B Lu, J Gong… - Journal of separation …, 2017 - Wiley Online Library
Gut microbiota–host cometabolites are closely related to various diseases. Monitoring
dynamic changes of cometabolites can provide a more comprehensive understanding of …

Screening gut microbial trimethylamine production by fast and cost-effective capillary electrophoresis

V García-Cañas, E Aznar, C Simó - Analytical and bioanalytical chemistry, 2019 - Springer
The present work is aimed to develop a simple, rapid, and cost-effective CE method for the
determination of trimethylamine (TMA) from bacterial origin. Optimum separation of TMA …

Multiplatform physiologic and metabolic phenotyping reveals microbial toxicity

J Cai, RG Nichols, I Koo, ZA Kalikow, L Zhang, Y Tian… - Msystems, 2018 - Am Soc Microbiol
The gut microbiota is susceptible to modulation by environmental stimuli and therefore can
serve as a biological sensor. Recent evidence suggests that xenobiotics can disrupt the …

An overview of metabolic phenotyping and its role in systems biology

E Holmes, ID Wilson, JC Lindon - The Handbook of Metabolic Phenotyping, 2019 - Elsevier
Understanding the functional relationships between genetic and gene expression variation
and real-world biochemical and physiological end points in human, animal, or plant …