Vascular calcification, which involves the deposition of calcifying particles within the arterial
wall, is mediated by atherosclerosis, vascular smooth muscle cell osteoblastic changes …

Background Sclerostin is an osteocyte-derived inhibitor of the Wnt pathway and has been
shown to play a key role in chronic kidney disease-mineral and bone disorder (CKD-MBD) …

The mechanism (s) mediating atherosclerotic calcification may be similar to those governing
bone remodeling, and osteoblast-like cells have been observed in plaque. We tested the …

Patients with chronic kidney disease‐mineral and bone disorder (CKD‐MBD) have a high
risk of bone fracture because of low bone mineral density and poor bone quality …

Conclusion A better understanding of the molecular mechanisms which are responsible for
cardiovascular calcification have led to a better detection and more adequate follow-up of …

Phosphorus is a vital element for life found in most foods as a natural component, but it is
also one of the most used preservatives added during food processing. High serum …

Osteocytes respond to kidney damage by increasing production of secreted factors
important to bone and mineral metabolism. These circulating proteins include the …

Objectives Dickkopf-1 (DKK1) is a potent inhibitor of Wnt signalling, which exerts anabolic
effects on bone and also takes part in the regulation of vascular cells. Our aims were to …

Abstract Ecto-5′-nucleotidase (e5NT, CD73) is an enzyme that is highly expressed in
endothelium and is involved in the extracellular nucleotide catabolism. CD73 converts AMP …

Vascular calcification and fragility fractures are associated with high morbidity and mortality,
especially in end-stage renal disease. We evaluated the relationship of iliac arteries …