As the global population becomes older, understanding the impact of aging on health and
disease becomes paramount. Recent advancements in multiomic technology have allowed …

Metabolomics is the latest state-of-the-art omics technology that provides a comprehensive
quantitative profile of metabolites. The metabolites are the cellular end products of metabolic …

To better understand the molecular mechanisms underpinning physiological variation in
human populations, metabolic phenotyping approaches are increasingly being applied to …

Chronological age is one of the most important risk factors for adverse clinical outcome. Still,
two individuals at the same chronological age could have different biological aging states …

Metabolomics is the latest 'omics' technology and systems biology science that allows for
comprehensive profiling of small-molecule metabolites in biological systems at a specific …

Quantitative plasma lipoprotein and metabolite profiles were measured on an autonomous
community of the Basque Country (Spain) cohort consisting of hospitalized COVID-19 …

Aging is a natural biological event that has some downsides such as increased frailty,
decline in cognitive and physical functions leading to chronical diseases, and lower quality …

The development of a chronic, low grade, inflammatory status named “inflammaging” is a
major characteristic of ageing, which plays a critical role in the pathogenesis of age-related …

Background: White matter hyperintensity (WMH) burden is associated with a higher risk of
ischemic stroke. Phenylacetylglutamine (PAGln) is a gut microbiota-derived metabolite that …

Background A greater understanding of mechanisms explaining the interactions between
diet and the gut microbiota in colorectal cancer is desirable. Genotoxic microbial metabolites …