[HTML][HTML] Significant risk of graft-versus-host disease with exposure to checkpoint inhibitors before and after allogeneic transplantation
Investigators are using checkpoint inhibitors (CPIs) to treat aggressive hematologic
malignancies in patients undergoing allogeneic hematopoietic stem cell transplantation (allo …
malignancies in patients undergoing allogeneic hematopoietic stem cell transplantation (allo …
Cytokines and costimulation in acute graft-versus-host disease
GR Hill, M Koyama - Blood, The Journal of the American …, 2020 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (alloSCT) is an important curative
therapy for high-risk hematological malignancies, but the development of severe and/or …
therapy for high-risk hematological malignancies, but the development of severe and/or …
Impaired T-and NK-cell reconstitution after haploidentical HCT with posttransplant cyclophosphamide
B Rambaldi, HT Kim, C Reynolds… - Blood …, 2021 - ashpublications.org
Administration of posttransplant cyclophosphamide (PTCy) has significantly expanded the
number of patients undergoing HLA-haploidentical hematopoietic cell transplantation (haplo …
number of patients undergoing HLA-haploidentical hematopoietic cell transplantation (haplo …
Allogeneic transplantation after PD-1 blockade for classic Hodgkin lymphoma
RW Merryman, L Castagna, L Giordano, VT Ho… - Leukemia, 2021 - nature.com
Anti-PD-1 monoclonal antibodies yield high response rates in patients with
relapsed/refractory classic Hodgkin lymphoma (cHL), but most patients will eventually …
relapsed/refractory classic Hodgkin lymphoma (cHL), but most patients will eventually …
Calcineurin inhibitor inhibits tolerance induction by suppressing terminal exhaustion of donor T cells after allo-HCT
H Senjo, S Harada, SI Kubota, Y Tanaka, T Tateno… - Blood, 2023 - ashpublications.org
Calcineurin inhibitor–based graft-versus-host disease (GVHD) prophylaxis is standard in
allogeneic hematopoietic stem cell transplantation (HCT) but fails to induce long-term …
allogeneic hematopoietic stem cell transplantation (HCT) but fails to induce long-term …
Improved outcomes for relapsed/refractory Hodgkin lymphoma after autologous transplantation in the era of novel agents
MA Spinner, RA Sica, JS Tamaresis… - Blood, The Journal …, 2023 - ashpublications.org
The treatment landscape of relapsed/refractory (R/R) classic Hodgkin lymphoma (cHL) has
evolved significantly over the past decade after the approval of brentuximab vedotin (BV) …
evolved significantly over the past decade after the approval of brentuximab vedotin (BV) …
Autologous stem cell transplantation after anti-PD-1 therapy for multiply relapsed or refractory Hodgkin lymphoma
RW Merryman, RA Redd, T Nishihori, J Chavez… - Blood …, 2021 - ashpublications.org
Autologous stem cell transplantation (ASCT) can be curative for patients with
relapsed/refractory Hodgkin lymphoma (HL). Based on studies suggesting that anti-PD-1 …
relapsed/refractory Hodgkin lymphoma (HL). Based on studies suggesting that anti-PD-1 …
[HTML][HTML] Lower graft-versus-host disease and relapse risk in post-transplant cyclophosphamide–based haploidentical versus matched sibling donor reduced-intensity …
Classic Hodgkin lymphoma (cHL) patients with relapsed or refractory disease may benefit
from allogeneic hematopoietic cell transplantation (allo-HCT), but many lack a matched …
from allogeneic hematopoietic cell transplantation (allo-HCT), but many lack a matched …
Single-center phase 2 study of PD-1 inhibitor combined with DNA hypomethylation agent+ CAG regimen in patients with relapsed/refractory acute myeloid leukemia
XN Gao, YF Su, M Li, Y Jing, J Wang, L Xu… - Cancer Immunology …, 2023 - Springer
Anti-PD-1 monotherapy had limited clinical efficacy in relapsed/refractory (r/r) AML patients
with higher PD-1 and PD-L1 expression. Hence, we investigated the efficacy and safety of …
with higher PD-1 and PD-L1 expression. Hence, we investigated the efficacy and safety of …
Optimizing outcomes in relapsed/refractory Hodgkin lymphoma: a review of current and forthcoming therapeutic strategies
TP Vassilakopoulos… - Therapeutic …, 2020 - journals.sagepub.com
The outcome of patients with relapsed/refractory classical Hodgkin lymphoma (rr-cHL) has
improved considerably in recent years owing to the approval of highly active novel agents …
improved considerably in recent years owing to the approval of highly active novel agents …