Engineered living materials: prospects and challenges for using biological systems to direct the assembly of smart materials
PQ Nguyen, NMD Courchesne… - Advanced …, 2018 - Wiley Online Library
Vast potential exists for the development of novel, engineered platforms that manipulate
biology for the production of programmed advanced materials. Such systems would possess …
biology for the production of programmed advanced materials. Such systems would possess …
Engineering stem cell self-organization to build better organoids
JA Brassard, MP Lutolf - Cell stem cell, 2019 - cell.com
Organoids form through self-organization processes in which initially homogeneous
populations of stem cells spontaneously break symmetry and undergo in-vivo-like pattern …
populations of stem cells spontaneously break symmetry and undergo in-vivo-like pattern …
Programming self-organizing multicellular structures with synthetic cell-cell signaling
A common theme in the self-organization of multicellular tissues is the use of cell-cell
signaling networks to induce morphological changes. We used the modular synNotch …
signaling networks to induce morphological changes. We used the modular synNotch …
Synthetic morphology with agential materials
Bioengineering can address many important needs, from transformative biomedicine to
environmental remediation. In addition to practical applications, the construction of new …
environmental remediation. In addition to practical applications, the construction of new …
Biological engineered living materials: growing functional materials with genetically programmable properties
C Gilbert, T Ellis - ACS synthetic biology, 2018 - ACS Publications
Natural biological materials exhibit remarkable properties: self-assembly from simple raw
materials, precise control of morphology, diverse physical and chemical properties, self …
materials, precise control of morphology, diverse physical and chemical properties, self …
Functional implications of intracellular phase transitions
AS Holehouse, RV Pappu - Biochemistry, 2018 - ACS Publications
Intracellular environments are heterogeneous milieus comprised of macromolecules,
osmolytes, and a range of assemblies that include membrane-bound organelles and …
osmolytes, and a range of assemblies that include membrane-bound organelles and …
A synthetic bacterial cell-cell adhesion toolbox for programming multicellular morphologies and patterns
DS Glass, IH Riedel-Kruse - Cell, 2018 - cell.com
Synthetic multicellular systems hold promise as models for understanding natural
development of biofilms and higher organisms and as tools for engineering complex multi …
development of biofilms and higher organisms and as tools for engineering complex multi …
Cell Surface Engineering Tools for Programming Living Assemblies
J Almeida‐Pinto, MR Lagarto, P Lavrador… - Advanced …, 2023 - Wiley Online Library
Breakthroughs in precision cell surface engineering tools are supporting the rapid
development of programmable living assemblies with valuable features for tackling complex …
development of programmable living assemblies with valuable features for tackling complex …
A comprehensive network atlas reveals that Turing patterns are common but not robust
Turing patterns (TPs) underlie many fundamental developmental processes, but they
operate over narrow parameter ranges, raising the conundrum of how evolution can ever …
operate over narrow parameter ranges, raising the conundrum of how evolution can ever …
Sculpting with stem cells: how models of embryo development take shape
During embryogenesis, organisms acquire their shape given boundary conditions that
impose geometrical, mechanical and biochemical constraints. A detailed integrative …
impose geometrical, mechanical and biochemical constraints. A detailed integrative …