Musculoskeletal tissues respond to optimal mechanical signals (eg, strains) through
anabolic adaptations, while mechanical signals above and below optimal levels cause …

Abstract Purpose of Review The patellofemoral joint is a complicated articulation of the
patella and femur that is prone to pathologies. The purpose of this review is to report on the …

Study Design Controlled laboratory study. Background The inclusion of specific exercises in
rehabilitation after knee injury is currently expert based, as a thorough description of the …

The generation of personalised and patient-specific musculoskeletal models is currently a
cumbersome and time-consuming task that normally requires several processing hours and …

Articular geometry in the knee varies widely among people which has implications for risk of
injury and pathology. The goals of this work were to develop a framework to systematically …

Cartilage is responsive to the loading imposed during cyclic routine activities. However, the
local relation between cartilage in terms of thickness distribution and biochemical …

Altered tibiofemoral contact forces represent a risk factor for osteoarthritis onset and
progression, making optimization of the knee force distribution a target of treatment …

Many studies have demonstrated covariation between muscle activations during behavior,
suggesting that muscles are not controlled independently. According to one common …

This study evaluates knee joint loading during gait and step-up-and-over tasks in control
subjects, subjects with early knee OA and those with established knee OA. Thirty-seven …

Injuries to the anterior cruciate ligament (ACL) and menisci commonly lead to early onset
osteoarthritis. Treatments that can restore normative cartilage loading patterns may mitigate …