Cancer is a general term for more than 100 unique malignancies in different organs of the
body. Each cancer type and subtype has its own unique genetic, epigenetic, and cellular …

Nuclear factor κB (NF-κB) acts as a nuclear factor that is composed of five main subunits. It is
a pluripotent and crucial dimer transcription factor that has a close relationship with many …

Breast cancer is the second leading primary cause for cancer‑related mortality among
women and metastasis to the brain is a disastrous event for patients with increasing …

Brian metastasis, which is diagnosed in 30% of triple-negative breast cancer (TNBC)
patients with metastasis, causes poor survival outcomes. Growing evidence has …

Background The aim of the study is described the regulatory mechanisms and prognostic
values of differentially expressed RNAs in prostate cancer and construct an mRNA signature …

Colorectal cancer is the third most common cancer worldwide, accounting for more than
610,000 mortalities every year. Prognosis of patients is highly dependent on the disease …

The present study aimed to investigate the role and mechanism of action of ribonucleotide
reductase M2 (RRM2) in lung adenocarcinoma and its potential as a therapeutic target. Data …

MircoRNA (miRNA), which are a group of small, and highly conserved non-coding RNA
consisting of 18-25 nucleotides, can modulate gene expression at post-transcriptional level …

Sirtuin 1 is one of the regulators of cell growth and survival and its inhibition is suggested as
a suitable mechanism to overcome breast cancer development. In this study we explored the …

Colorectal cancer (CRC) is one of the most prevalent diseases worldwide; however, the
molecular mechanisms involved in CRC remain unclear. Thus, we aimed to explore a novel …