Oligodendrocytes and Alzheimer's disease

Z Cai, M Xiao - International Journal of Neuroscience, 2016 - Taylor & Francis
Extensive evidence has indicated that the breakdown of myelin is associated with
Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's …

Cerebral hypoxia: its role in age-related chronic and acute cognitive dysfunction

B Snyder, SM Simone, T Giovannetti… - Anesthesia & …, 2021 - journals.lww.com
Postoperative cognitive dysfunction (POCD) has been reported with widely varying
frequency but appears to be strongly associated with aging. Outside of the surgical arena …

Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer's and Parkinson's …

L Danielyan, S Beer-Hammer, A Stolzing… - Cell …, 2014 - journals.sagepub.com
In view of the rapid preclinical development of cell-based therapies for neurodegenerative
disorders, traumatic brain injury, and tumors, the safe and efficient delivery and targeting of …

Taking aim at Alzheimer's disease through the mammalian target of rapamycin

K Maiese - Annals of medicine, 2014 - Taylor & Francis
A significant portion of the world's population suffers from sporadic Alzheimer's disease (AD)
with available present therapies limited to symptomatic care that does not alter disease …

brain penetrating bifunctional erythropoietin–transferrin receptor antibody fusion protein for Alzheimer's disease

R Chang, A Al Maghribi, V Vanderpoel… - Molecular …, 2018 - ACS Publications
Erythropoietin (EPO), a glycoprotein cytokine essential to hematopoiesis, has
neuroprotective effects in rodent models of Alzheimer's disease (AD). However, high …

[HTML][HTML] Regeneration in the nervous system with erythropoietin

K Maiese - Frontiers in bioscience (Landmark edition), 2016 - ncbi.nlm.nih.gov
Globally, greater than 30 million individuals are afflicted with disorders of the nervous
system accompanied by tens of thousands of new cases annually with limited, if any …

[HTML][HTML] Losartan improves memory, neurogenesis and cell motility in transgenic Alzheimer's mice

HJ Drews, R Klein, A Lourhmati, M Buadze… - Pharmaceuticals, 2021 - mdpi.com
Angiotensin receptor blockers (ARBs) have demonstrated multiple neuroprotective benefits
in Alzheimer's disease (AD) models. However, their beneficial effects on memory deficits …

[HTML][HTML] Neuroprotective effects of erythropoietin on neurodegenerative and ischemic brain diseases: the role of erythropoietin receptor

CC Hernández, CF Burgos, AH Gajardo… - Neural regeneration …, 2017 - journals.lww.com
Erythropoietin (Epo) is a fundamental hormone in the regulation of hematopoiesis, and other
secondary roles mediated by the binding of the hormone to its specific receptor (EpoR) …

[HTML][HTML] Erythropoietin and diabetes mellitus

K Maiese - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Abstract Erythropoietin (EPO) is a 30.4 kDa growth factor and cytokine that governs cell
proliferation, immune modulation, metabolic homeostasis, vascular function, and …

Erythropoietin and mTOR: a “one-two punch” for aging-related disorders accompanied by enhanced life expectancy

K Maiese - Current neurovascular research, 2016 - ingentaconnect.com
Life expectancy continues to increase throughout the world, but is accompanied by a rise in
the incidence of non-communicable diseases. As a result, the benefits of an increased …