Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …

Antimicrobial peptides are an attractive alternative to traditional antibiotics, due to their
physicochemical properties, activity toward a broad spectrum of bacteria, and mode-of …

Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …

Bacterial resistance and excessive inflammation are common issues that hinder wound
healing. Antimicrobial peptides (AMPs) offer a promising and versatile antibacterial option …

Gram-negative bacteria release vesicular structures from their outer membrane, so called
outer membrane vesicles (OMVs). OMVs have a variety of functions such as waste disposal …

Rapid antimicrobial action is an important advantage of antimicrobial peptides (AMPs) over
antibiotics, which is also a reason for AMPs being less likely to induce bacterial resistance …

The human cathelicidin LL-37 serves a critical role in the innate immune system defending
bacterial infections. LL-37 can interact with molecules of the cell wall and perforate …