[HTML][HTML] CRISPR-Cas system: from diagnostic tool to potential antiviral treatment

A Rajan, S Shrivastava, Janhawi, A Kumar… - Applied Microbiology …, 2022 - Springer
This mini review focuses on the diagnosis and treatment of virus diseases using Crisper-Cas
technology. The present paper describes various strategies involved in diagnosing diseases …

[HTML][HTML] Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection

Z Cui, C Zeng, F Huang, F Yuan, J Yan, Y Zhao… - Nature chemical …, 2022 - nature.com
SARS-CoV-2 entry into cells requires specific host proteases; however, no successful in vivo
applications of host protease inhibitors have yet been reported for treatment of SARS-CoV-2 …

[HTML][HTML] Seven classes of antiviral agents

A Ianevski, S Ahmad, K Anunnitipat… - Cellular and Molecular …, 2022 - Springer
The viral epidemics and pandemics have stimulated the development of known and the
discovery of novel antiviral agents. About a hundred mono-and combination antiviral drugs …

[HTML][HTML] XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection

PP Gerber, MJ Donde, NJ Matheson… - Nature …, 2022 - nature.com
The unprecedented emergence and spread of SARS-CoV-2, the coronavirus responsible for
the COVID-19 pandemic, underscores the need for diagnostic and therapeutic technologies …

[HTML][HTML] Lipid-coated mesoporous silica nanoparticles for anti-viral applications via delivery of CRISPR-Cas9 ribonucleoproteins

AE LaBauve, EA Saada, IKA Jones, R Mosesso… - Scientific reports, 2023 - nature.com
Emerging and re-emerging viral pathogens present a unique challenge for anti-viral
therapeutic development. Anti-viral approaches with high flexibility and rapid production …

[HTML][HTML] Advances in Editing Silkworms (Bombyx mori) Genome by Using the CRISPR-Cas System

GM Baci, AA Cucu, AI Giurgiu, AS Muscă, L Bagameri… - Insects, 2021 - mdpi.com
Simple Summary One of the most powerful gene editing approaches is the CRISPR
(clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) tool …

[HTML][HTML] The convergent evolution of influenza A virus: Implications, therapeutic strategies and what we need to know

ZY Low, KH Wong, AJW Yip, WS Choo - Current Research in Microbial …, 2023 - Elsevier
Influenza virus infection, more commonly known as the 'cold flu', is an etiological agent that
gives rise to recurrent annual flu and many pandemics. Dated back to the 1918-Spanish Flu …

[HTML][HTML] Engineering CRISPR/Cas13 system against RNA viruses: from diagnostics to therapeutics

Y Xue, Z Chen, W Zhang, J Zhang - Bioengineering, 2022 - mdpi.com
Over the past decades, RNA viruses have been threatened people's health and led to global
health emergencies. Significant progress has been made in diagnostic methods and …

[HTML][HTML] Principles and applications of CRISPR toolkit in virus manipulation, diagnosis, and virus-host interactions

S Jamehdor, S Pajouhanfar, S Saba, G Uzan… - Cells, 2022 - mdpi.com
Viruses are one of the most important concerns for human health, and overcoming viral
infections is a worldwide challenge. However, researchers have been trying to manipulate …

[HTML][HTML] Precision in Action: The Role of Clustered Regularly Interspaced Short Palindromic Repeats/Cas in Gene Therapies

A Banda, O Impomeni, A Singh, AR Baloch, W Hu… - Vaccines, 2024 - mdpi.com
Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated enzyme-
CAS holds great promise for treating many uncured human diseases and illnesses by …