Arterial stiffness and cardiovascular risk in hypertension

P Boutouyrie, P Chowienczyk, JD Humphrey… - Circulation …, 2021 - Am Heart Assoc
Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or
structural levels, with the latter combining effects of the geometry and composition of the …

Aortic stiffness: current understanding and future directions

JL Cavalcante, JAC Lima, A Redheuil… - Journal of the American …, 2011 - jacc.org
The aorta stiffens with aging, a process that is accelerated by arterial hypertension.
Decreased arterial compliance is one of the earliest detectable manifestations of adverse …

Beta‐blockers for hypertension

CS Wiysonge, HA Bradley, J Volmink… - Cochrane database …, 2017 - cochranelibrary.com
Background Beta‐blockers refer to a mixed group of drugs with diverse pharmacodynamic
and pharmacokinetic properties. They have shown long‐term beneficial effects on mortality …

Association of estimated pulse wave velocity with survival: a secondary analysis of SPRINT

C Vlachopoulos, D Terentes-Printzios… - JAMA network …, 2019 - jamanetwork.com
Importance Aortic stiffness, as assessed by carotid-femoral pulse wave velocity, is an
independent predictor of future events in individuals with hypertension. Recent data suggest …

Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension

IS Mackenzie, CM McEniery, Z Dhakam, MJ Brown… - …, 2009 - Am Heart Assoc
Isolated systolic hypertension is an important risk factor for cardiovascular disease and
results primarily from elastic artery stiffening. Although various drug therapies are used to …

[HTML][HTML] The year in hypertension

B Williams - Journal of the American College of Cardiology, 2009 - jacc.org
The year 2008 was extraordinary because of the number of reports from major clinical
outcome trials of blood pressure (BP)-lowering therapies. Consequently, this review of the …

Arterial aging—hemodynamic changes and therapeutic options

ME Safar - Nature Reviews Cardiology, 2010 - nature.com
Arterial aging can be attributed to two different pathophysiological changes—increase in
arterial stiffness and disturbed wave reflections. The capacity of the aorta to absorb the force …

Effects of antihypertensive drugs on arterial stiffness

T Dudenbostel, SP Glasser - Cardiology in review, 2012 - journals.lww.com
In this review, we discuss the possible pathophysiological mechanisms and the role of
arterial stiffness as a biomarker, a blood pressure–independent predictor of cardiovascular …

Increased arterial stiffness in resistant hypertension is associated with inflammatory biomarkers

NR Barbaro, V Fontana, R Modolo, AP De Faria… - Blood …, 2015 - Taylor & Francis
Background. Increased levels of inflammatory biomarkers such as interleukin-6 (IL-6), 10 (IL-
10), 1β (IL-1β), tumor necrosis factor-α (TNF-α) high-sensitivity C-reactive protein (hs-CRP) …

Aortic stiffness: pathophysiology, clinical implications, and approach to treatment

S Sethi, O Rivera, R Oliveros… - Integrated blood pressure …, 2014 - Taylor & Francis
Aortic stiffness is a hallmark of aging, and classic cardiovascular risk factors play a role in
accelerating this process. Current changes in medicine, which focus on preventive care …