[HTML][HTML] The role of cell death in SARS-CoV-2 infection
C Yuan, Z Ma, J Xie, W Li, L Su, G Zhang, J Xu… - Signal transduction and …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …
[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …
first documented pandemic due to a coronavirus that continues to be a major health …
Evolution of the SARS-CoV-2 mutational spectrum
SARS-CoV-2 evolves rapidly in part because of its high mutation rate. Here, we examine
whether this mutational process itself has changed during viral evolution. To do this, we …
whether this mutational process itself has changed during viral evolution. To do this, we …
[HTML][HTML] Prevalence and functional profile of SARS-CoV-2 T cells in asymptomatic Kenyan adults
T Samandari, JB Ongalo, KD McCarthy… - The Journal of …, 2023 - Am Soc Clin Investig
Background SARS-CoV-2 infection in Africa has been characterized by a less severe
disease profile than what has been observed elsewhere, but the profile of SARS-CoV-2 …
disease profile than what has been observed elsewhere, but the profile of SARS-CoV-2 …
Endoplasmic reticulum-associated SARS-CoV-2 ORF3a elicits heightened cytopathic effects despite robust ER-associated degradation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORF3a protein plays a vital
role in viral pathogenesis and coronavirus disease 2019 (COVID-19). Like the spike protein …
role in viral pathogenesis and coronavirus disease 2019 (COVID-19). Like the spike protein …
Evolution of ACE2-independent SARS-CoV-2 infection and mouse adaption after passage in cells expressing human and mouse ACE2
Human ACE2 Human angiotensin converting enzyme 2 (hACE2) is the key cell attachment
and entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with …
and entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with …
SARS‐CoV‐2, aging, and Post‐COVID‐19 neurodegeneration
MJ Strong - Journal of Neurochemistry, 2023 - Wiley Online Library
As the world continues to experience the effects of SARS‐CoV‐2, there is evidence to
suggest that the sequelae of viral infection (the post‐COVID‐19 condition; PCC) at both an …
suggest that the sequelae of viral infection (the post‐COVID‐19 condition; PCC) at both an …
[HTML][HTML] Role of NLRP3 inflammasome in diabetes and COVID-19 role of NLRP3 inflammasome in the pathogenesis and treatment of COVID-19 and diabetes NLRP3 …
J Zhang, X Ma, F Liu, D Zhang, J Ling, Z Zhu… - Frontiers in …, 2023 - frontiersin.org
2019 Coronavirus Disease (COVID-19) is a global pandemic caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2). A “cytokine storm”, ie, elevated levels of …
respiratory syndrome coronavirus-2 (SARS-CoV-2). A “cytokine storm”, ie, elevated levels of …
SARS‐CoV‐2 ORF3a expression in brain disrupts the autophagy–lysosomal pathway, impairs sphingolipid homeostasis, and drives neuropathogenesis
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection causes injury to
multiple organ systems, including the brain. SARS‐CoV‐2's neuropathological mechanisms …
multiple organ systems, including the brain. SARS‐CoV‐2's neuropathological mechanisms …
[HTML][HTML] Channel activity of SARS-CoV-2 viroporin ORF3a inhibited by adamantanes and phenolic plant metabolites
MS Fam, CA Sedky, NO Turky, HG Breitinger… - Scientific reports, 2023 - nature.com
SARS-CoV-2 has been responsible for the major worldwide pandemic of COVID-19. Despite
the enormous success of vaccination campaigns, virus infections are still prevalent and …
the enormous success of vaccination campaigns, virus infections are still prevalent and …