An update on generalized pustular psoriasis

MJ Gooderham, AS Van Voorhees… - Expert review of clinical …, 2019 - Taylor & Francis
Introduction: Generalized pustular psoriasis (GPP) is a rare, severe relapsing/remitting,
multisystem disease that can be difficult to treat. Recent clinical, histological, and genetic …

[HTML][HTML] Pathophysiology of generalized pustular psoriasis

S Marrakchi, L Puig - American Journal of Clinical Dermatology, 2022 - Springer
Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis
characterized by widespread, recurrent episodes of neutrophil-rich pustule formation in the …

[HTML][HTML] Trial of spesolimab for generalized pustular psoriasis

H Bachelez, SE Choon, S Marrakchi… - … England Journal of …, 2021 - Mass Medical Soc
Background Generalized pustular psoriasis (GPP) is a rare, life-threatening, inflammatory
skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 …

Efficacy and safety of subcutaneous spesolimab for the prevention of generalised pustular psoriasis flares (Effisayil 2): an international, multicentre, randomised …

A Morita, B Strober, AD Burden, SE Choon, MJ Anadkat… - The Lancet, 2023 - thelancet.com
Background Spesolimab is an anti-interleukin-36 receptor monoclonal antibody approved to
treat generalised pustular psoriasis (GPP) flares. We aimed to assess the efficacy and safety …

Prevalence, comorbidities and mortality of generalized pustular psoriasis: a literature review

JC Prinz, SE Choon, CEM Griffiths… - Journal of the …, 2023 - Wiley Online Library
Generalized pustular psoriasis (GPP) is a rare auto‐inflammatory skin disease characterised
by acute episodes of sterile pustule formation. Diagnosis and treatment of the disease have …

Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion

H Bachelez, J Barker, AD Burden… - Expert Review of …, 2022 - Taylor & Francis
Introduction Generalized pustular psoriasis (GPP) is a rare, severe, clinically heterogeneous
disease characterized by flares of widespread, noninfectious, macroscopically visible …

[HTML][HTML] Treatment options and goals for patients with generalized pustular psoriasis

J Krueger, L Puig, D Thaçi - American Journal of Clinical Dermatology, 2022 - Springer
Generalized pustular psoriasis (GPP) is a rare, severe neutrophilic skin disorder
characterized by sudden widespread eruption of superficial sterile pustules with or without …

Treatments and outcomes of generalized pustular psoriasis: a cohort of 1516 patients in a nationwide inpatient database in Japan

H Miyachi, T Konishi, R Kumazawa, H Matsui… - Journal of the American …, 2022 - Elsevier
Background Because generalized pustular psoriasis (GPP) is rare, there are few studies
reporting treatments and outcomes for large numbers of patients. Objective To report …

[HTML][HTML] Diagnosis of generalized pustular psoriasis

H Fujita, M Gooderham, R Romiti - American Journal of Clinical …, 2022 - Springer
Generalized pustular psoriasis (GPP) is a severe rare skin disease characterized by
widespread eruption of sterile superficial macroscopic pustules with or without systemic …

Current management of generalized pustular psoriasis

N Kodali, I Blanchard, S Kunamneni… - Experimental …, 2023 - Wiley Online Library
Generalized pustular psoriasis (GPP) is a rare subset of psoriasis involving episodes of
sterile pustules accompanied by inflammation and, often, systemic involvement. The …