Reactive nitrogen species (RNS) and reactive oxygen species (ROS), collectively known as
reactive oxygen and nitrogen species (RONS), are the products of normal cellular …

Nitric oxide (NO) is a short-lived, endogenously produced, signaling molecule which plays
multiple roles in mammalian physiology. Underproduction of NO is associated with several …

The year 2021 is the 100th anniversary of the confirmation of the neurotransmission
phenomenon by Otto Loewi. Over the course of the hundred years, about 100 …

Iron, the most abundant transition metal ion in humans, participates in the biosynthesis,
translocation, signal transduction, and transformation of nitric oxide through its …

Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes
such as cellular metabolism, vasodilation and transmission of nerve impulses. A wide …

As a therapeutic group, non-steroidal anti-inflammatory drugs (NSAIDs) are among the most
widely used, prescribed and over the counter (OTC) medications for the treatment of …

Current trends and characteristic examples of recent advances in syntheses of practically
important compounds bearing semi-polar nitrogen–oxygen bonds (NO-systems) are …

Among the variety of nitrogen heterocycles, the furoxan (1, 2, 5-oxadiazole 2-oxide) scaffold
has attracted considerable attention owing to its ability to release NO under physiological …

A novel one‐pot cascade method for the assembly of valuable NO‐donor azasydnone
scaffold has been developed. The construction strategy involves a diazotization/azo …

Ketoprofen belongs to one of the most common nonsteroidal anti‐inflammatory drugs
(NSAIDs) but its clinical usefulness has been restricted due to the high incidence of …