Clinical decision support improves blood culture collection before intravenous antibiotic administration in the emergency department

S Dutta, DS McEvoy, DM Rubins… - Journal of the …, 2022 - academic.oup.com
Abstract Objective Surviving Sepsis guidelines recommend blood cultures before
administration of intravenous (IV) antibiotics for patients with sepsis or moderate to high risk …

Next-generation sequencing diagnostics of bacteremia in pediatric sepsis

T Schmoch, JH Westhoff, SO Decker, A Skarabis… - Medicine, 2021 - journals.lww.com
Methods: The Next GeneSiPS-Trial is a prospective, observational, non-interventional,
multicenter study used to assess the diagnostic performance of an NGS-based approach for …

Management of neutropenic patients in the intensive care unit (NEWBORNS EXCLUDED) recommendations from an expert panel from the French Intensive Care …

D Schnell, E Azoulay, D Benoit, B Clouzeau… - Annals of intensive …, 2016 - Springer
Neutropenia is defined by either an absolute or functional defect (acute myeloid leukemia or
myelodysplastic syndrome) of polymorphonuclear neutrophils and is associated with high …

[HTML][HTML] De-escalation and discontinuation of empirical antibiotic treatment in a cohort of allogeneic hematopoietic stem cell transplantation recipients during the pre …

G Gustinetti, AM Raiola, R Varaldo, F Galaverna… - Biology of Blood and …, 2018 - Elsevier
To investigate rates and outcomes of antibiotic de-escalation during pre-engraftment
neutropenia in allogeneic hematopoietic stem cell transplantation (HSCT) recipients. 110 …

Antibiotic indications and appropriateness in the pediatric intensive care unit: a 10-center point prevalence study

K Chiotos, J Blumenthal, J Boguniewicz… - Clinical Infectious …, 2023 - academic.oup.com
Background Antibiotics are prescribed to most pediatric intensive care unit (PICU) patients,
but data describing indications and appropriateness of antibiotic orders in this population …

Antimicrobial de-escalation in the ICU: from recommendations to level of evidence

I Lakbar, JJ De Waele, A Tabah, S Einav… - Advances in …, 2020 - Springer
Antimicrobial de-escalation (ADE) is a component of antimicrobial stewardship (AMS) aimed
to reduce exposure to broad-spectrum antimicrobials. In the intensive care unit, ADE is a …

Clinical impact of procalcitonin-based algorithms for duration of antibiotic treatment in critically ill adult patients with sepsis: a meta-analysis of randomized clinical …

A Gutiérrez-Pizarraya, MDC Leon-Garcia… - Expert Review of Anti …, 2022 - Taylor & Francis
Background Our objective was to assess the impact on mortality, antibacterial therapy
duration, and length of stay of using PCT to guide antibiotic cessation in critically ill patients …

Procalcitonin (PCT)-guided antibiotic stewardship in Asia-Pacific countries: adaptation based on an expert consensus meeting

CC Lee, ALH Kwa, A Apisarnthanarak… - Clinical Chemistry and …, 2020 - degruyter.com
Introduction Recently, an expert consensus on optimal use of procalcitonin (PCT)-guided
antibiotic stewardship was published focusing mainly on Europe and the United States …

[HTML][HTML] Clindamycin but not intravenous immunoglobulins reduces mortality in a retrospective cohort of critically ill patients with bacteremic group A streptococcal …

A Fernández-Galilea, Á Estella… - Revista Española de …, 2022 - ncbi.nlm.nih.gov
Clindamycin but not Intravenous Immunoglobulins reduces mortality in a retrospective cohort
of critically ill patients with bacteremic Group A Streptococcal infections - PMC Back to Top …

Impact of immunosuppression on incidence, aetiology and outcome of ventilator-associated lower respiratory tract infections

AS Moreau, I Martin-Loeches, P Povoa… - European …, 2018 - Eur Respiratory Soc
The aim of this planned analysis of the prospective multinational TAVeM database was to
determine the incidence, aetiology and impact on outcome of ventilator-associated lower …