Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise
classification. It is often considered as part of the global overview of functional somatic …

What is the little button for? This button is pushed at bedtime and awake time to let the
research know what time you went to bed and got up. This button can also be used with the …

In humans, the secretion of cortisol from the adrenal glands follows a diurnal cycle with a
profound increase after awakening. This increase after awakening, a phenomenon termed …

The magnitude of the cortisol awakening response, a relatively new indicator of
hypothalamic–pituitary–adrenocortical (HPA) axis activation, has been related to a number …

Objective. This review highlights research on sex-based differences in pain perception and
treatment. We sought to illuminate the complex factors contributing to differences in pain and …

BACKGROUND: Preclinical research findings suggest that exposure to stress and
concomitant hypothalamus-pituitary-adrenal (HPA) axis activation during early development …

Rationale Abuse and neglect are highly prevalent in children and have enduring
neurobiological effects. Stressful early life environments perturb the hypothalamic–pituitary …

Objective We examined the association between retrospective reports of adverse childhood
experiences (ACEs) and painful medical conditions. We also examined the mediating and …

Trauma is a precursor to many mental health conditions that greatly impact victims, their
loved ones, and society. Studies indicate that neurobiological associations with adverse …