Oral nanomedicine: challenges and opportunities

B Deng, S Liu, Y Wang, B Ali, N Kong, T Xie… - Advanced …, 2024 - Wiley Online Library
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Cardiovascular disease and cancer: shared risk factors and mechanisms

NS Wilcox, U Amit, JB Reibel, E Berlin… - Nature Reviews …, 2024 - nature.com
Cardiovascular disease (CVD) and cancer are among the leading causes of morbidity and
mortality globally, and these conditions are increasingly recognized to be fundamentally …

[HTML][HTML] Characterization of Wnt signaling pathway under treatment of Lactobacillus acidophilus postbiotic in colorectal cancer using an integrated in silico and in vitro …

N Erfanian, S Nasseri, A Miraki Feriz, H Safarpour… - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) is a prevalent and life-threatening cancer closely associated with
the gut microbiota. Probiotics, as a vital microbiota group, interact with the host's colonic …

[HTML][HTML] Crosstalk between gut microbiota and metastasis in colorectal cancer: Implication of neutrophil extracellular traps

J Wu, W Dong, Y Pan, J Wang, M Wu, Y Yu - Frontiers in Immunology, 2023 - frontiersin.org
Primary colorectal cancer (CRC) often leads to liver metastasis, possibly due to the
formation of pre-metastatic niche (PMN) in liver. Thus, unravelling the key modulator in …

Therapeutic phage monitoring: a review

K Bosco, S Lynch, I Sandaradura… - Clinical Infectious …, 2023 - academic.oup.com
With the global rise in antimicrobial resistance, there has been a renewed interest in the
application of therapeutic phages to treat bacterial infections. Therapeutic phage monitoring …

[HTML][HTML] Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human …

F Li, X Ling, S Chakraborty, C Fountzilas… - Journal of Experimental …, 2023 - Springer
There is increasing evidence indicating the significant role of DDX5 (also called p68), acting
as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation …

[HTML][HTML] EphA2 as a phase separation protein associated with ferroptosis and immune cell infiltration in colorectal cancer

Y Li, Q Peng, L Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Colorectal cancer is one of the most common malignant tumors in the digestive system, and
its high incidence and metastasis rate make it a terrible killer that threatens human health. In …

Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease

C Chen, A Beloqui, Y Xu - Advanced drug delivery reviews, 2023 - Elsevier
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …

The microbiome and rise of early-onset cancers: knowledge gaps and research opportunities

K Mima, T Hamada, K Inamura, H Baba, T Ugai… - Gut …, 2023 - Taylor & Francis
Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

Lifestyle and host determinants of antitumor immunity and cancer health disparities

A Swaby, A Atallah, O Varol, A Cristea, DF Quail - Trends in Cancer, 2023 - cell.com
Lifestyle factors exert profound effects on host physiology and immunology. Disparities in
cancer outcomes persist as a complex and multifaceted challenge, necessitating a …