Prognostic and predictive factors in oral cancer: the role of the invasive tumour front

A Bankfalvi, J Piffko - Journal of Oral Pathology & Medicine …, 2000 - Wiley Online Library
Most decisions for cancer patients are now made on the basis of prognostic and predictive
factors. However, due to the limited prognostic value of conventional tumour/nodal …

Combretastatin A4 phosphate

CML West, P Price - Anti-cancer drugs, 2004 - journals.lww.com
Abstract Combretastatin A4 phosphate (CA4P) is a water-soluble prodrug of combretastatin
A4 (CA4). The vascular targeting agent CA4 is a microtubule depolymerizing agent. The …

Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo

I Hartlapp, R Abe, RW Saeed, T Peng… - The FASEB …, 2001 - Wiley Online Library
Angiogenesis is an ordered process requiring the inter‐play of numerous cellular and
humoral factors. Studies over the past 20 years have identified several growth factors …

Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization

M Stassar, G Devitt, M Brosius, L Rinnab… - British journal of …, 2001 - nature.com
Renal cell carcinoma (RCC) are frequently chemo-and radiation resistant. Thus, there is a
need for identifying biological features of these cells that could serve as alternative …

Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the progression of …

E Obermueller, S Vosseler, NE Fusenig, MM Mueller - Cancer research, 2004 - AACR
Tumor growth and progression are critically controlled by alterations in the
microenvironment often caused by an aberrant expression of growth factors and receptors …

A phase I study of anti-kinase insert domain-containing receptor antibody, IMC-1C11, in patients with liver metastases from colorectal carcinoma

JA Posey, TC Ng, B Yang, MB Khazaeli… - Clinical cancer …, 2003 - AACR
Purpose: Angiogenesis plays an important role in colorectal cancer progression. Stimulation
of vascular endothelial growth factor receptor (VEGFR), a transmembrane glycoprotein …

Genes that regulate metastasis and angiogenesis

CP Webb, GF Vande Woude - Journal of neuro-oncology, 2000 - Springer
Genetic instability and an accumulation of genetic and epigenetic changes during tumor
progression lead to an increasingly aggressive and treatment-resistant phenotype, and …

Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK

HA Dbouk, LM Weil, GKS Perera… - Proceedings of the …, 2014 - National Acad Sciences
The with no lysine (K)(WNK) family of enzymes is best known for control of blood pressure
through regulation of the function and membrane localization of ion cotransporters. In mice …

[PDF][PDF] Myofibroblast induction and microvascular alteration in scleroderma lung fibrosis

M Beon, RA Harley, A Wessels, RM Silver… - Clin Exp …, 2004 - clinexprheumatol.org
Objective Scleroderma (SSc) is an autoimmune connective tissue disorder characterized by
progressive fibrosis of the skin and internal organs. The leading cause of death in SSc …

Gene therapy for prostate cancer: current status and future prospects

KJ Harrington, C Spitzweg, AR Bateman, JC Morris… - The Journal of …, 2001 - Elsevier
PURPOSE: Locally advanced, relapsed and metastatic prostate cancer has a dismal
prognosis with conventional therapies offering no more than palliation. In recent years …