Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
[HTML][HTML] Extracellular vesicles and nanoparticles: emerging complexities
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …
because recent discoveries have revealed a much greater complexity and diversity than was …
MicroRNA sequence codes for small extracellular vesicle release and cellular retention
Exosomes and other small extracellular vesicles (sEVs) provide a unique mode of cell-to-
cell communication in which microRNAs (miRNAs) produced and released from one cell are …
cell communication in which microRNAs (miRNAs) produced and released from one cell are …
[HTML][HTML] Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
QF Han, WJ Li, KS Hu, J Gao, WL Zhai, JH Yang… - Molecular cancer, 2022 - Springer
Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …
various physiological and pathological processes. Their biogenesis involves four key steps …
[HTML][HTML] Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Extracellular vesicles and exomere nanoparticles are under intense investigation as sources
of clinically relevant cargo. Here we report the discovery of a distinct extracellular …
of clinically relevant cargo. Here we report the discovery of a distinct extracellular …
[PDF][PDF] Exosomes as mediators of intercellular crosstalk in metabolism
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
Aptamer-based detection of circulating targets for precision medicine
L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …
[HTML][HTML] Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liver metastasis of colorectal cancer
S Zhao, Y Mi, B Guan, B Zheng, P Wei, Y Gu… - Journal of hematology & …, 2020 - Springer
Background Mounting evidence has demonstrated the vital importance of tumor-associated
macrophages (TAMs) and exosomes in the formation of the premetastatic niche. However …
macrophages (TAMs) and exosomes in the formation of the premetastatic niche. However …
[HTML][HTML] EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3
Z Pan, R Zhao, B Li, Y Qi, W Qiu, Q Guo, S Zhang… - Molecular cancer, 2022 - Springer
Background Gliomas are the most common malignant primary brain tumours with a highly
immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs …
immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs …
[HTML][HTML] RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …