Long non-coding RNAs: Tools for understanding and targeting cancer pathways

GK Pandey, C Kanduri - Cancers, 2022 - mdpi.com
Simple Summary Long non-coding RNA (lncRNA) is a type of RNA molecule that show
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …

Long non-coding RNAs, extracellular vesicles and inflammation in Alzheimer's disease

A Canseco-Rodriguez, V Masola, V Aliperti… - International Journal of …, 2022 - mdpi.com
Alzheimer's Disease (AD) has currently no effective treatment; however, preventive
measures have the potential to reduce AD risk. Thus, accurate and early prediction of risk is …

The interplay between noncoding RNAs and drug resistance in hepatocellular carcinoma: the big impact of little things

Y Fang, XL Zhang, HF Huang, Z Zeng - Journal of Translational Medicine, 2023 - Springer
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death in people, and
a common primary liver cancer. Lacking early diagnosis and a high recurrence rate after …

Long non-coding RNAs in cancer: multifaceted roles and potential targets for immunotherapy

LK Kadian, D Verma, N Lohani, R Yadav… - Molecular and cellular …, 2024 - Springer
Cancer remains a major global health concern with high mortality rates mainly due to late
diagnosis and poor prognosis. Long non-coding RNAs (lncRNAs) are emerging as key …

LncRNA/miRNA/mRNA network introduces novel biomarkers in prostate cancer

M Taheri, A Safarzadeh, BM Hussen, S Ghafouri-Fard… - Cells, 2022 - mdpi.com
The construction of a competing endogenous RNA (ceRNA) network is an important step in
the identification of the role of differentially expressed genes in cancers. In the current …

LncRNA weighted gene co-expression network analysis reveals novel biomarkers related to prostate cancer metastasis

M Liu, MY Chen, JM Huang, Q Liu, L Wang, R Liu… - BMC medical …, 2022 - Springer
Background Most prostate cancer patients die from metastasis and lack accurate efficacious
biomarkers to monitor the disease behavior, optimize treatment and assess prognosis …

Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer

M Taheri, E Badrlou, BM Hussen, AH Kashi… - Frontiers in …, 2023 - frontiersin.org
Long non-coding RNAs (lncRNAs) are regulatory transcripts with essential roles in the
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …

[HTML][HTML] Predicting prostate cancer progression with a Multi-lncRNA expression-based risk score and nomogram integrating ISUP grading

S Ledesma-Bazan, F Cascardo, J Bizzotto… - Non-coding RNA …, 2024 - Elsevier
Prostate cancer is a highly heterogeneous disease; therefore, estimating patient prognosis
accurately is challenging due to the lack of biomarkers with sufficient specificity and …

[HTML][HTML] Transcript Markers from Urinary Extracellular Vesicles for Predicting Risk Reclassification of Prostate Cancer Patients on Active Surveillance

K Erdmann, F Distler, S Gräfe, J Kwe, HHH Erb… - Cancers, 2024 - mdpi.com
Simple Summary Active surveillance is the preferred treatment strategy for low-risk prostate
cancer and includes regular monitoring by control biopsies, which bear the risk of various …

Novel PRUNE2 Germline Mutations in Aggressive and Benign Parathyroid Neoplasms

S Storvall, E Ryhänen, A Karhu, C Schalin-Jäntti - Cancers, 2023 - mdpi.com
Simple Summary Recently, PRUNE2 mutations were indicated in the pathogenesis of
aggressive parathyroid neoplasms. Here, we report novel, rare PRUNE2 mutations located …