BACKGROUND Primary ciliary dyskinesia (PCD) is a genetic condition affecting the
structure and function of sperm flagellum and motile cilia including those in the male and …

Discerning the genetics and epigenetics of chronic rhinosinusitis (CRS) may optimize
outcomes through early diagnostics, personalized and novel therapeutics, and early …

Nasal nitric oxide (nNO) is extremely low in most people with primary ciliary dyskinesia
(PCD) and its measurement is an important contributor to making the diagnosis. Existing …

Abstract Background and Objective Primary ciliary dyskinesia (PCD) is a rare genetic
disorder causing a defective ciliary structure, which predominantly leads to an impaired …

Background and objectives Primary ciliary dyskinesia (PCD, ORPHA: 244) is a group of rare
genetic disorders characterized by dysfunction of motile cilia. It is phenotypically and …

Primary ciliary dyskinesia (PCD) is a rare, genetic disease characterized by dysfunctional
motile cilia and abnormal mucociliary clearance, resulting in chronic sino-oto-pulmonary …

Tubulin, one of the most abundant cytoskeletal building blocks, has numerous isotypes in
metazoans encoded by different conserved genes. Whether these distinct isotypes form cell …

Children with inherited and/or acquired respiratory disorders often arrive in adolescence
and adulthood with diminished lung function that might have been detected and prevented …

Primary ciliary dyskinesia (PCD) is a hereditary disease caused by pathogenic variants in
genes associated with motile cilia. Some variants responsible for PCD are reported to be …

Background Primary ciliary dyskinesia (PCD) is typically an autosomal recessive disease
characterized by recurrent infections of the lower respiratory tract, frequent and severe otitis …