LOX-1 in atherosclerosis: biological functions and pharmacological modifiers

S Xu, S Ogura, J Chen, PJ Little, J Moss… - Cellular and Molecular Life …, 2013 - Springer
Lectin-like oxidized LDL (oxLDL) receptor-1 (LOX-1, also known as OLR-1), is a class E
scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved …

[HTML][HTML] Consolidated and emerging inflammatory markers in coronary artery disease

V Lubrano, S Balzan - World journal of experimental medicine, 2015 - ncbi.nlm.nih.gov
Coronary artery disease is an event of atherosclerosis characterized by a chronic vascular
inflammation. Risk factors like obesity, diabetes mellitus, hypertension, smoking …

[HTML][HTML] COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches

AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The current coronavirus disease 2019 (COVID‐19) pandemic presents a global challenge
for managing acutely ill patients and complications from viral infection. Systemic …

[HTML][HTML] Atherosclerotic cardiovascular disease risk assessment: An American Society for Preventive Cardiology clinical practice statement

ND Wong, MJ Budoff, K Ferdinand, IM Graham… - American journal of …, 2022 - Elsevier
Risk for atherosclerotic cardiovascular disease (ASCVD) shows considerable heterogeneity
both in generally healthy persons and in those with known ASCVD. The foundation of …

Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes

S Kraler, FA Wenzl, G Georgiopoulos… - European heart …, 2022 - academic.oup.com
Aims The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and its shedding
product [soluble LOX-1 (sLOX-1)] are implicated in atherosclerotic cardiovascular disease …

The changes of immunoglobulin G N-glycosylation in blood lipids and dyslipidaemia

D Liu, X Chu, H Wang, J Dong, SQ Ge, ZY Zhao… - Journal of translational …, 2018 - Springer
Background Alternative N-glycosylation has significant structural and functional
consequences on immunoglobulin G (IgG) and can affect immune responses, acting as a …

LOX-1 and ROS, inseparable factors in the process of endothelial damage

V Lubrano, S Balzan - Free Radical Research, 2014 - Taylor & Francis
Lectin-like oxidized low-density lipoprotein (LOX-1) has been identified in endothelial cells
as the main receptor of oxidized low-density lipoprotein (OxLDL). LOX-1 is upregulated in …

Soluble LOX‐1: a novel biomarker in patients with coronary artery disease, stroke, and acute aortic dissection?

A Hofmann, C Brunssen, S Wolk, C Reeps… - Journal of the …, 2020 - Am Heart Assoc
Cardiovascular diseases are the leading cause of death worldwide. Approximately 85% of
all deaths from cardiovascular disease are due to acute myocardial infarction (AMI) and …

Role of oxidative stress-related biomarkers in heart failure: galectin 3, α1-antitrypsin and LOX-1: new therapeutic perspective?

V Lubrano, S Balzan - Molecular and cellular biochemistry, 2020 - Springer
Heart failure (HF) is considered one of the most common diseases and one of the major
causes of death. The latest studies show that HF is associated with an increase in oxidative …

High plasma levels of soluble lectin‐like oxidized low‐density lipoprotein receptor‐1 are associated with inflammation and cardiometabolic risk profiles in pediatric …

SE Stinson, AE Jonsson, MK Andersen… - Journal of the …, 2023 - Am Heart Assoc
Background Lectin‐like oxidized low‐density lipoprotein (ox‐LDL) receptor‐1 is a scavenger
receptor for oxidized low‐density lipoprotein. In adults, higher soluble lectin‐like ox‐LDL …