Spatiotemporal manipulation metal–organic frameworks as oral drug delivery systems for precision medicine

Z Wang, J Chen, R Gao, L Jiang, G Zhang… - Coordination Chemistry …, 2024 - Elsevier
Oral drug administration is the preferred method for delivering medications due to its safety,
ease of ingestion, high patient compliance, absence of pain, and adaptability to a wide …

[HTML][HTML] Oral delivery of RNAi for cancer therapy

H Afrin, R Geetha Bai, R Kumar, SS Ahmad… - Cancer and Metastasis …, 2023 - Springer
Cancer is a major health concern worldwide and is still in a continuous surge of seeking for
effective treatments. Since the discovery of RNAi and their mechanism of action, it has …

[HTML][HTML] Delivery of biologics: Topical administration

RJ Kulchar, R Singh, S Ding, E Alexander, KW Leong… - Biomaterials, 2023 - Elsevier
Biologics are unaffordable to a large majority of the global population because of
prohibitively expensive fermentation systems, purification and the requirement for cold chain …

Multifaceted roles of pollen in the management of cancer

T Kolipaka, P Khairnar, V Phatale, G Pandey… - International Journal of …, 2023 - Elsevier
Oral drug delivery of microparticles demonstrates shortcomings like aggregation, decreased
loading capacity and batch-to-batch variation, which limits its scale-up. Later, porous …

Development and challenges of antimicrobial peptide delivery strategies in bacterial therapy: A review

L Yao, Q Liu, Z Lei, T Sun - International Journal of Biological …, 2023 - Elsevier
The escalating global prevalence of antimicrobial resistance poses a critical threat,
prompting concerns about its impact on public health. This predicament is exacerbated by …

Pharmacokinetics and pharmacodynamics of cyclodextrin-based oral drug delivery formulations for disease therapy

H Liu, S Guo, S Wei, J Liu, B Tian - Carbohydrate Polymers, 2024 - Elsevier
Oral drug administration has become the most common and preferred mode of disease
treatment due to its good medication adherence and convenience. For orally administered …

Recent progress of micro/nanomotors to overcome physiological barriers in the gastrointestinal tract

S Zhang, C Zhu, W Huang, H Liu, M Yang… - Journal of Controlled …, 2023 - Elsevier
Oral administration is a convenient administration route for gastrointestinal disease therapy
with good patient compliance. But the nonspecific distribution of the oral drugs may cause …

Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease

C Chen, A Beloqui, Y Xu - Advanced drug delivery reviews, 2023 - Elsevier
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …

[HTML][HTML] PH-responsive and mucoadhesive nanoparticles for enhanced oral insulin delivery: the effect of hyaluronic acid with different molecular weights

S Wang, S Meng, X Zhou, Z Gao, MG Piao - Pharmaceutics, 2023 - mdpi.com
Drug degradation at low pH and rapid clearance from intestinal absorption sites are the
main factors limiting the development of oral macromolecular delivery systems. Based on …

[HTML][HTML] Liposome-derived nanosystems for the treatment of behavioral and neurodegenerative diseases: the promise of niosomes, transfersomes, and ethosomes for …

PC Pires, AC Paiva-Santos, F Veiga - Pharmaceuticals, 2023 - mdpi.com
Psychiatric and neurodegenerative disorders are amongst the most prevalent and
debilitating diseases, but current treatments either have low success rates, greatly due to the …