Mesenchymal stem cells for regenerative medicine

Y Han, X Li, Y Zhang, Y Han, F Chang, J Ding - Cells, 2019 - mdpi.com
In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have
attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and …

Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

Y Shi, Y Wang, Q Li, K Liu, J Hou, C Shao… - Nature Reviews …, 2018 - nature.com
Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …

Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612

L Ge, C Xun, W Li, S Jin, Z Liu, Y Zhuo, D Duan… - Journal of …, 2021 - Springer
Mesenchymal stem cells (MSCs) play important roles in tissue repair and regeneration, such
as the induction of angiogenesis, particularly under hypoxic conditions. However, the …

Cancer stem cells in renal cell carcinoma: origins and biomarkers

F Lasorsa, M Rutigliano, M Milella, M Ferro… - International Journal of …, 2023 - mdpi.com
The term “cancer stem cell”(CSC) refers to a cancer cell with the following features:
clonogenic ability, the expression of stem cell markers, differentiation into cells of different …

Ischemia-reperfusion injury reduces long term renal graft survival: mechanism and beyond

H Zhao, A Alam, AP Soo, AJT George, D Ma - EBioMedicine, 2018 - thelancet.com
Ischemia-reperfusion injury (IRI) during renal transplantation often initiates non-specific
inflammatory responses that can result in the loss of kidney graft viability. However, the long …

Mesenchymal stem cell‐based therapy for kidney disease: a review of clinical evidence

AJ Peired, A Sisti, P Romagnani - Stem cells international, 2016 - Wiley Online Library
Mesenchymal stem cells form a population of self‐renewing, multipotent cells that can be
isolated from several tissues. Multiple preclinical studies have demonstrated that the …

Strategies to optimize adult stem cell therapy for tissue regeneration

S Liu, J Zhou, X Zhang, Y Liu, J Chen, B Hu… - International journal of …, 2016 - mdpi.com
Stem cell therapy aims to replace damaged or aged cells with healthy functioning cells in
congenital defects, tissue injuries, autoimmune disorders, and neurogenic degenerative …

Nestin regulates cellular redox homeostasis in lung cancer through the Keap1–Nrf2 feedback loop

J Wang, Q Lu, J Cai, Y Wang, X Lai, Y Qiu… - Nature …, 2019 - nature.com
Abnormal cancer antioxidant capacity is considered as a potential mechanism of tumor
malignancy. Modulation of oxidative stress status is emerging as an anti-cancer treatment …

Mesenchymal stem cell subpopulations: phenotype, property and therapeutic potential

M Mo, S Wang, Y Zhou, H Li, Y Wu - Cellular and Molecular Life Sciences, 2016 - Springer
Mesenchymal stem cells (MSC) are capable of differentiating into cells of multiple cell
lineages and have potent paracrine effects. Due to their easy preparation and low …

Conductive biomaterials as substrates for neural stem cells differentiation towards neuronal lineage cells

M Farokhi, F Mottaghitalab, MR Saeb… - Macromolecular …, 2021 - Wiley Online Library
The injuries and defects in the central nervous system are the causes of disability and death
of an affected person. As of now, there are no clinically available methods to enhance neural …