Signalling cognition: the gut microbiota and hypothalamic-pituitary-adrenal axis

JA Rusch, BT Layden, LR Dugas - Frontiers in endocrinology, 2023 - frontiersin.org
Cognitive function in humans depends on the complex and interplay between multiple body
systems, including the hypothalamic-pituitary-adrenal (HPA) axis. The gut microbiota, which …

Are the epigenetic changes predictive of therapeutic efficacy for psychiatric disorders? A translational approach towards novel drug targets

V Micale, M Di Bartolomeo, S Di Martino, T Stark… - Pharmacology & …, 2023 - Elsevier
The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …

[HTML][HTML] Effects of lavender on anxiety, depression, and physiological parameters: Systematic review and meta-analysis

M Kim, ES Nam, Y Lee, HJ Kang - Asian nursing research, 2021 - Elsevier
Purpose The recent evidence suggested substantial anxiolytic efficacy of lavender. The aim
of this study was to examine the efficacy of lavender for anxiety, depression, and …

The endocannabinoid system and physical exercise

D Matei, D Trofin, DA Iordan, I Onu… - International journal of …, 2023 - mdpi.com
The endocannabinoid system (ECS) is involved in various processes, including brain
plasticity, learning and memory, neuronal development, nociception, inflammation, appetite …

Effect of heat stress on growth and production performance of livestock and poultry: Mechanism to prevention

S Chen, Y Yong, X Ju - Journal of Thermal Biology, 2021 - Elsevier
Heat stress is a widespread phenomenon in domestic animal feeding in tropical and sub-
tropical areas that are subjected to a growing negative effect in livestock and poultry due to …

Reviewing the role of the endocannabinoid system in the pathophysiology of depression

I Gallego-Landin, A Garcia-Baos… - Frontiers in …, 2021 - frontiersin.org
Major depressive disorder is a high-impact, debilitating disease and it is currently
considered the most prevalent mental illness. It is associated with disability, as well as …

Major phytocannabinoids and their related compounds: should we only search for drugs that act on cannabinoid receptors?

LE Filipiuc, DC Ababei, T Alexa-Stratulat, CV Pricope… - Pharmaceutics, 2021 - mdpi.com
The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …

Emerging therapeutic potential of cannabidiol (CBD) in neurological disorders: a comprehensive review

K Singh, B Bhushan, DK Chanchal… - Behavioural …, 2023 - Wiley Online Library
Cannabidiol (CBD), derived from Cannabis sativa, has gained remarkable attention for its
potential therapeutic applications. This thorough analysis explores the increasing …

Endocannabinoid system: chemical characteristics and biological activity

B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

The effects of trauma on brain and body: A unifying role for the midbrain periaqueductal gray

BA Terpou, S Harricharan… - Journal of …, 2019 - Wiley Online Library
Post‐traumatic stress disorder (PTSD), a diagnosis that may follow the experience of trauma,
has multiple symptomatic phenotypes. Generally, individuals with PTSD display symptoms …