It is becoming increasingly clear that suboptimal blood glucose control results in adverse
effects on large blood vessels, thereby accelerating atherosclerosis and cardiovascular …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The majority of
cardiovascular complications are secondary to atherosclerosis. Extensive evidence has …

The prevalence of atherosclerotic disease continues to increase, and despite significant
reductions in major cardiovascular events with current medical interventions, an additional …

C-reactive protein (CRP) has been suggested to directly induce the inflammatory response
leading to the progression of atherosclerosis. However, recent in vitro studies raised the …

Insulin-like growth factor-1 (IGF-1) signaling is important for the maintenance of plaque
stability in atherosclerosis due to its effects on vascular smooth muscle cell (vSMC) …

The role of vasa vasorum (VV) in atherosclerosis is hotly debated, and new experimental
techniques have recently opened an opportunity to take a fresh look at this important topic …

Over the past decade, studies have repeatedly found single-nucleotide polymorphisms
located in the collagen (COL) 4A1 and COL4A2 genes to be associated with cardiovascular …

Aims Neutrophil gelatinase-associated lipocalin (NGAL) is an effector molecule of the innate
immune system. One of its actions is the prolongation of matrix metalloproteinase-9 (MMP-9) …

Purpose Dabigatran etexilate (DE) constitutes a novel, direct thrombin inhibitor. Regarding
the association of thrombin with atherogenesis, we assessed the effects of DE on the …

Context: Matrix metalloproteinases are involved in atherosclerosis and plaque vulnerability.
Objective: To investigate serum levels and genetic polymorphisms of matrix …