ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders

V Singh, R Kaur, P Kumari, C Pasricha, R Singh - Clinica Chimica Acta, 2023 - Elsevier
Leukocyte migration from the vascular compartment is critical for normal lymphocyte
recirculation in specific tissues and immune response in inflammatory locations. Leukocyte …

Molecules promoting circulating clusters of cancer cells suggest novel therapeutic targets for treatment of metastatic cancers

JM Rozenberg, AA Buzdin, T Mohammad… - Frontiers in …, 2023 - frontiersin.org
Treatment of metastatic disease remains among the most challenging tasks in oncology.
One of the early events that predicts a poor prognosis and precedes the development of …

Tumor-derived biomarkers in liquid biopsy of glioblastoma

V Khristov, A Lin, Z Freedman, J Staub, G Shenoy… - World neurosurgery, 2023 - Elsevier
There is a pressing clinical need for minimally invasive liquid biopsies to supplement
imaging in the treatment of glioblastoma. Diagnostic imaging is often difficult to interpret and …

The complexity of immune evasion mechanisms throughout the metastatic cascade

NM Haynes, TB Chadwick, BS Parker - Nature Immunology, 2024 - nature.com
Metastasis, the spread of cancer from a primary site to distant organs, is an important
challenge in oncology. This Review explores the complexities of immune escape …

Prospects of liquid biopsy in the prognosis and clinical management of gastrointestinal cancers

D Mondal, S Shinde, V Sinha, V Dixit, S Paul… - Frontiers in Molecular …, 2024 - frontiersin.org
Gastrointestinal (GI) cancers account for one-fourth of the global cancer incidence and are
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …

The role of hypoxia and radiation in developing a CTCs-like phenotype in murine osteosarcoma cells

M Quartieri, A Puspitasari, T Vitacchio… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Cancer treatment has evolved significantly, yet concerns about tumor
recurrence and metastasis persist. Within the dynamic tumor microenvironment, a …

From the catastrophic objective irreproducibility of cancer research and unavoidable failures of molecular targeted therapies to the sparkling hope of supramolecular …

I Alekseenko, L Kondratyeva, I Chernov… - International Journal of …, 2023 - mdpi.com
The unprecedented non-reproducibility of the results published in the field of cancer
research has recently come under the spotlight. In this short review, we try to highlight some …

Capture of circulating metastatic cancer cell clusters from lung cancer patients can reveal unique genomic profiles and potential anti-metastatic molecular targets: A …

K Kouhmareh, E Martin, D Finlay, A Bhadada… - Plos one, 2024 - journals.plos.org
Metastasis remains the leading cause of cancer deaths worldwide and lung cancer, known
for its highly metastatic progression, remains among the most lethal of malignancies. Lung …

[HTML][HTML] CTC-neutrophil interaction: A key driver and therapeutic target of cancer metastasis

C Hu, L Long, J Lou, M Leng, Q Yang, X Xu… - Biomedicine & …, 2024 - Elsevier
Circulating tumor cells (CTCs) are cancer cells that detach from the primary tumor and enter
the bloodstream, where they can seed new metastatic lesions in distant organs. CTCs are …

The emerging role of liquid biopsy in oral squamous cell carcinoma detection: advantages and challenges

S Gupta, B Singh, R Abhishek, S Gupta… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Oral Squamous Cell Carcinoma (OSCC), the sixth most widespread
malignancy in the world, accounts for 90% of all cases of oral cancer. The primary risk …