[HTML][HTML] Mechanisms of oxidative stress in metabolic syndrome

SK Masenga, LS Kabwe, M Chakulya… - International journal of …, 2023 - mdpi.com
Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …

[HTML][HTML] The role of adipokines in health and disease

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2023 - mdpi.com
Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

The effects of protein corona on in vivo fate of nanocarriers

Q Xiao, M Zoulikha, M Qiu, C Teng, C Lin, X Li… - Advanced Drug Delivery …, 2022 - Elsevier
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …

The angiotensin AT2 receptor: from a binding site to a novel therapeutic target

UM Steckelings, RE Widdop, ED Sturrock… - Pharmacological …, 2022 - ASPET
Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from
a binding site with unknown function to a firmly established major effector within the …

[HTML][HTML] Use of physical activity and exercise to reduce inflammation in children and adolescents with obesity

V Calcaterra, M Vandoni, V Rossi, C Berardo… - International Journal of …, 2022 - mdpi.com
Childhood obesity is a leading public health problem worldwide, as it is increasingly
prevalent and therefore responsible for serious obesity-related comorbidities, not only in …

[HTML][HTML] Obesity and bone health: a complex link

J Hou, C He, W He, M Yang, X Luo, C Li - Frontiers in cell and …, 2020 - frontiersin.org
So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …

[HTML][HTML] Lipotoxicity and diabetic nephropathy: novel mechanistic insights and therapeutic opportunities

L Opazo-Ríos, S Mas, G Marín-Royo… - International journal of …, 2020 - mdpi.com
Lipotoxicity is characterized by the ectopic accumulation of lipids in organs different from
adipose tissue. Lipotoxicity is mainly associated with dysfunctional signaling and insulin …

[HTML][HTML] There is urgent need to treat atherosclerotic cardiovascular disease risk earlier, more intensively, and with greater precision: A review of current practice and …

ME Makover, MD Shapiro, PP Toth - American Journal of Preventive …, 2022 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) is epidemic throughout the world and is
etiologic for such acute cardiovascular events as myocardial infarction, ischemic stroke …

[HTML][HTML] Coffee or tea: Anti-inflammatory properties in the context of atherosclerotic cardiovascular disease prevention

S Surma, A Sahebkar, M Banach - Pharmacological Research, 2023 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of premature death
worldwide. Inflammation and its biomarkers, like C-reactive protein (CRP), among the risk …

[HTML][HTML] GPR84-mediated signal transduction affects metabolic function by promoting brown adipocyte activity

XN Sun, YA An, VA Paschoal… - The Journal of …, 2023 - Am Soc Clin Investig
The G protein–coupled receptor 84 (GPR84), a medium-chain fatty acid receptor, has
garnered attention because of its potential involvement in a range of metabolic conditions …