Psoriasis is a common chronic inflammatory skin disease, associated with substantial
comorbidity. TH17 lymphocytes, differentiating under the influence of dendritic cell-derived …

Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …

Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognize microbial
metabolites through a semi-invariant T cell receptor (TCR). Major questions remain …

Chronic kidney disease (CKD) is inherently an inflammatory condition, which ultimately
results in the development of end stage renal disease or cardiovascular events. Low-grade …

Background The effectiveness of available biologics for the treatment of hidradenitis
suppurativa (HS) is limited. Additional therapeutic options are needed. Objectives To …

Trillions of beneficial and hostile microorganisms live in the human respiratory and
gastrointestinal tracts, which act as gatekeepers in maintaining human health, ie, protecting …

Objective The importance of interleukin‐17A (IL‐17A) in the pathogenesis of axial
spondyloarthritis (SpA) has been demonstrated by the success of IL‐17A blockade …

The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial
roles in host defence against microbial organisms and the development of inflammatory …

Axial spondyloarthritis (axial-SpA) is a multifactorial disease characterized by inflammation
in sacroiliac joints and spine, bone reabsorption, and aberrant bone deposition, which may …

Abstract Mucosal-associated Invariant T (MAIT) cells are an innate-like T cell subset that
recognize a broad array of microbial pathogens, including respiratory pathogens. Here we …