The effects of metals as endocrine disruptors

I Iavicoli, L Fontana, A Bergamaschi - Journal of Toxicology and …, 2009 - Taylor & Francis
This review reports current knowledge regarding the roles that cadmium (Cd), mercury (Hg),
arsenic (As), lead (PB), manganese (Mn), and zinc (Zn) play as endocrine-disrupting …

Vitellogenin as a biomarker of exposure to estrogenic compounds in aquatic invertebrates: a review

V Matozzo, F Gagné, MG Marin, F Ricciardi… - Environment …, 2008 - Elsevier
Vitellogenins (Vg) are the major precursor of the egg-yolk proteins, vitellins (Vn), which
provide energy reserves for embryonic development in oviparous organisms. In mature …

Epigenetic transgenerational actions of endocrine disruptors and male fertility

MD Anway, AS Cupp, M Uzumcu, MK Skinner - science, 2005 - science.org
Transgenerational effects of environmental toxins require either a chromosomal or
epigenetic alteration in the germ line. Transient exposure of a gestating female rat during the …

Oestrogenic activity of parabens in MCF7 human breast cancer cells

JR Byford, LE Shaw, MGB Drew, GS Pope… - The Journal of steroid …, 2002 - Elsevier
Parabens (4-hydroxybenzoic acid esters) have been recently reported to have oestrogenic
activity in yeast cells and animal models. Since the human population is exposed to …

Estrogenic endocrine-disrupting chemicals: molecular mechanisms of actions on putative human diseases

K Yoon, SJ Kwack, HS Kim, BM Lee - Journal of Toxicology and …, 2014 - Taylor & Francis
Endocrine-disrupting chemicals (EDC), including phthalates, bisphenol A (BPA),
phytoestrogens such as genistein and daidzein, dichlorodiphenyltrichloroethane (DDT), and …

Toxicological characteristics of endocrine-disrupting chemicals: developmental toxicity, carcinogenicity, and mutagenicity

SM Choi, SD Yoo, BM Lee - Journal of Toxicology and …, 2004 - Taylor & Francis
It is generally accepted that endocrine-disrupting chemicals (EDCs) play a role in a variety of
adverse health effects in an intact organism or its progeny as a consequence of changes in …

Transgenerational effect of the endocrine disruptor vinclozolin on male spermatogenesis

MD Anway, MA Memon, M Uzumcu… - Journal of …, 2006 - Wiley Online Library
The current study was designed to examine the actions of a model endocrine disruptor on
embryonic testis development and male fertility. Pregnant rats (F0) that received a transient …

Estrogens and environmental estrogens

H Tapiero, GN Ba, KD Tew - Biomedicine & pharmacotherapy, 2002 - Elsevier
The natural female sex hormone estrogens binds once inside the cell to a protein receptor to
form a 'ligand-hormone receptor complex'. The binding activates the hormone receptor …

Oestrogenic activity of p‐hydroxybenzoic acid (common metabolite of paraben esters) and methylparaben in human breast cancer cell lines

D Pugazhendhi, GS Pope… - Journal of Applied …, 2005 - Wiley Online Library
This paper addresses the question of whether p‐hydroxybenzoic acid, the common
metabolite of parabens, possesses oestrogenic activity in human breast cancer cell lines …

Human exposure to endocrine disrupters and semen quality

KP Phillips, N Tanphaichitr - Journal of Toxicology and …, 2008 - Taylor & Francis
Reproductive pathology in the male represents about 20% of infertility cases. Male infertility
may be attributed to a number of causes, including genetic and congenital abnormalities …