Revisiting neoadjuvant therapy in non-small-cell lung cancer

SPL Saw, BH Ong, KLM Chua, A Takano… - The Lancet …, 2021 - thelancet.com
Despite the rapidly evolving treatment landscape in advanced non-small-cell lung cancer
(NSCLC), developments in neoadjuvant and adjuvant treatments have been nascent by …

[HTML][HTML] Radiation-induced lung toxicity–cellular and molecular mechanisms of pathogenesis, management, and literature review

L Käsmann, A Dietrich, CA Staab-Weijnitz… - Radiation …, 2020 - Springer
Lung, breast, and esophageal cancer represent three common malignancies with high
incidence and mortality worldwide. The management of these tumors critically relies on …

Total-body PET/CT using half-dose FDG and compared with conventional PET/CT using full-dose FDG in lung cancer

H Tan, X Sui, H Yin, H Yu, Y Gu, S Chen, P Hu… - European journal of …, 2021 - Springer
Purpose The purpose was to explore the effects of total-body PET/CT with half-dose 18 F-
FDG activity on image quality, compared with those of conventional PET/CT with clinical …

[HTML][HTML] Demystifying the results of RTOG 0617: identification of dose sensitive cardiac subregions associated with overall survival

A McWilliam, A Abravan, K Banfill, C Faivre-Finn… - Journal of Thoracic …, 2023 - Elsevier
Introduction The RTOG 0617 trial presented a worse survival for patients with lung cancer
treated in the high-dose (74 Gy) arm. In multivariable models, radiation level and whole …

Randomized phase III trial of metabolic imaging-guided dose escalation of radio-chemotherapy in patients with newly diagnosed glioblastoma (SPECTRO GLIO trial)

A Laprie, G Noel, L Chaltiel, G Truc… - Neuro …, 2024 - academic.oup.com
Background Glioblastoma (GBM) systematically recurs after a standard 60 Gy radio-
chemotherapy regimen. Since magnetic resonance spectroscopic imaging (MRSI) has been …

[HTML][HTML] Joint EANM/SNMMI/ESTRO practice recommendations for the use of 2-[18F]FDG PET/CT external beam radiation treatment planning in lung cancer V1.0

SC Vaz, JA Adam, RCD Bolton, P Vera… - European journal of …, 2022 - Springer
Abstract Purpose 2-[18 F] FDG PET/CT is of utmost importance for radiation treatment (RT)
planning and response monitoring in lung cancer patients, in both non-small and small cell …

Expert consensus on oncological [18F]FDG total-body PET/CT imaging (version 1)

H Yu, Y Gu, W Fan, Y Gao, M Wang, X Zhu, Z Wu… - European …, 2023 - Springer
Background [18F] FDG imaging on total-body PET/CT (TB PET/CT) scanners, with improved
sensitivity, offers new potentials for cancer diagnosis, staging, and radiation treatment …

Impact of 68Ga-FAPI PET/CT on staging and oncologic management in a cohort of 226 patients with various cancers

SA Koerber, M Röhrich, L Walkenbach… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Since the development of fibroblast activation protein–targeted radiopharmaceuticals, 68Ga-
fibroblast activation protein inhibitor (FAPI) PET/CT has been found to be suitable for …

18F-FDG-PET guided vs whole tumour radiotherapy dose escalation in patients with locally advanced non-small cell lung cancer (PET-Boost): Results from a …

SA Cooke, D de Ruysscher, B Reymen… - Radiotherapy and …, 2023 - Elsevier
Background and purpose We aimed to assess if radiation dose escalation to either the
whole primary tumour, or to an 18 F-FDG-PET defined subvolume within the primary tumour …

Grand challenges for medical physics in radiation oncology

C Fiorino, R Jeraj, CH Clark, C Garibaldi… - Radiotherapy and …, 2020 - Elsevier
Medical physics has made considerable contributions to recent advances in radiation
oncology. Medical physicists are key players in the clinical and scientific radiation oncology …