Early diagnosis of pancreatic cancer: clinical premonitions, timely precursor detection and increased curative-intent surgery

K Søreide, W Ismail, M Roalsø, J Ghotbi… - Cancer …, 2023 - journals.sagepub.com
Background The overall poor prognosis in pancreatic cancer is related to late clinical
detection. Early diagnosis remains a considerable challenge in pancreatic cancer …

Plasma extracellular vesicle long RNA profiling identifies a diagnostic signature for the detection of pancreatic ductal adenocarcinoma

S Yu, Y Li, Z Liao, Z Wang, Z Wang, Y Li, L Qian… - Gut, 2020 - gut.bmj.com
Objective Pancreatic ductal adenocarcinoma (PDAC) is difficult to diagnose at resectable
stage. Recent studies have suggested that extracellular vesicles (EVs) contain long RNAs …

[HTML][HTML] Pancreatic cancer diagnosis and management: has the time come to prick the bubble?

P Moutinho-Ribeiro, G Macedo, SA Melo - Frontiers in endocrinology, 2019 - frontiersin.org
Pancreatic cancer (PC) is associated with poor prognosis and very dismal survival rates.
The most effective possibility of cure is tumor resection, which is only possible in about 15 …

Efficacy of extended versus standard lymphadenectomy in pancreatoduodenectomy for pancreatic head adenocarcinoma. An update meta-analysis

W Wang, Y He, L Wu, L Ye, L Yao, Z Tang - Pancreatology, 2019 - Elsevier
Background Surgical resection is the only possible cure for pancreatic cancer, it remains
controversial whether extend lymphadenectomy in pancreatoduodenectomy (EPD) is better …

[HTML][HTML] Early detection of pancreatic cancer: the role of depression and anxiety as a precursor for disease

BJ Kenner - Pancreas, 2018 - journals.lww.com
Receiving a diagnosis of cancer is known to cause depression in the patient due to the
challenges and uncertainty this diagnosis brings. Anecdotal reports of depression before a …

Clinical Effect of Driver Mutations of KRAS, CDKN2A/P16, TP53, and SMAD4 in Pancreatic Cancer: A Meta-Analysis

Y Gu, Y Ji, H Jiang, G Qiu - Genetic Testing and Molecular …, 2020 - liebertpub.com
Objective: To evaluate the prognostic value of driver mutations in the KRAS, CDKN2A/P16,
TP53, and SMAD4 genes in pancreatic cancer to aid in the design of therapeutic strategies …

Early pancreatic cancer—The role of endoscopic ultrasound with or without tissue acquisition in diagnosis and staging

P Moutinho-Ribeiro, J Iglesias-Garcia, R Gaspar… - Digestive and Liver …, 2019 - Elsevier
Pancreatic cancer (PC) is one of the deadliest cancers with a 5-year overall survival of less
than 6%. Due to its insidious clinical course and unspecific symptoms, the diagnosis is …

[HTML][HTML] Diagnostic strategy of early stage pancreatic cancer via clinical predictor assessment: clinical indicators, risk factors and imaging findings

R Sagami, T Sato, K Mizukami, M Motomura… - Diagnostics, 2022 - mdpi.com
Early detection of pancreatic ductal adenocarcinoma (PDAC) in the general population is
difficult due to unknown clinical characteristics. This study was conducted to clarify the …

Accuracy of Fukuoka and American Gastroenterological Association guidelines for predicting advanced neoplasia in pancreatic cyst neoplasm: a meta-analysis

J Wu, Y Wang, Z Li, H Miao - Annals of Surgical Oncology, 2019 - Springer
Background A differential diagnosis of advanced pancreatic cystic neoplasms (PCNs) is
critical to determine optimal treatment. The Fukuoka and American Gastroenterological …

[HTML][HTML] Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound …

P Moutinho-Ribeiro, IA Batista, ST Quintas… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Individuals within specific risk groups for pancreatic ductal adenocarcinoma
(PDAC)[mucinous cystic lesions (MCLs), hereditary risk (HR), and new-late onset diabetes …