Role of catalase in oxidative stress‐and age‐associated degenerative diseases

A Nandi, LJ Yan, CK Jana, N Das - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive species produced in the cell during normal cellular metabolism can chemically
react with cellular biomolecules such as nucleic acids, proteins, and lipids, thereby causing …

Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

[HTML][HTML] NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's …

MW Park, HW Cha, J Kim, JH Kim, H Yang, S Yoon… - Redox biology, 2021 - Elsevier
Oxidative stress has been implicated in the pathogenesis of Alzheimer's disease (AD).
Mitochondrial dysfunction is linked to oxidative stress and reactive oxygen species (ROS) in …

[HTML][HTML] Chemical basis of reactive oxygen species reactivity and involvement in neurodegenerative diseases

F Collin - International journal of molecular sciences, 2019 - mdpi.com
Increasing numbers of individuals suffer from neurodegenerative diseases, which are
characterized by progressive loss of neurons. Oxidative stress, in particular, the …

[HTML][HTML] Oxidative stress and the amyloid beta peptide in Alzheimer's disease

C Cheignon, M Tomas, D Bonnefont-Rousselot… - Redox biology, 2018 - Elsevier
Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

ROS-scavenging therapeutic hydrogels for modulation of the inflammatory response

YE Kim, J Kim - ACS applied materials & interfaces, 2021 - ACS Publications
Although reactive oxygen species (ROS) are essential for cellular processes, excessive
ROS could be a major cause of various inflammatory diseases because of the oxidation of …

[HTML][HTML] Neuroprotective natural products for Alzheimer's disease

X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

A Redox Modulatory Mn3O4 Nanozyme with Multi‐Enzyme Activity Provides Efficient Cytoprotection to Human Cells in a Parkinson's Disease Model

N Singh, MA Savanur, S Srivastava… - Angewandte …, 2017 - Wiley Online Library
Nanomaterials with enzyme‐like activities (nanozymes) attracts significant interest due to
their therapeutic potential for the treatment of various diseases. Herein, we report that a …

[HTML][HTML] Role of oxidative stress in Alzheimer's disease

WJ Huang, XIA Zhang, WW Chen - Biomedical reports, 2016 - spandidos-publications.com
Alzheimer's disease (AD) is the most common cause of disability in individuals aged> 65
years worldwide. AD is characterized by the abnormal deposition of amyloid β (Aβ) peptide …

The role of antioxidants in the chemistry of oxidative stress: A review

AM Pisoschi, A Pop - European journal of medicinal chemistry, 2015 - Elsevier
Abstract This Review Article is focused on the action of the reactive oxygenated species in
inducing oxidative injury of the lipid membrane components, as well as on the ability of …