[HTML][HTML] Oral adjuvant curcumin therapy for attaining clinical remission in ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials

MG Grammatikopoulou, K Gkiouras, X Theodoridis… - Nutrients, 2018 - mdpi.com
Curcumin has demonstrated anti-inflammatory properties and has been investigated as an
adjuvant therapy of ulcerative colitis (UC). The scope of this study was to systematically …

Antifibrotic drug use in patients with idiopathic pulmonary fibrosis. Data from the IPF-PRO Registry

ML Salisbury, CS Conoscenti, DA Culver… - Annals of the …, 2020 - atsjournals.org
Rationale: Two antifibrotic medications, nintedanib and pirfenidone, have been approved for
the treatment of idiopathic pulmonary fibrosis (IPF) in the United States. Few data have been …

Current therapeutic strategies for respiratory diseases using mesenchymal stem cells

M Wang, T Zhou, Z Zhang, H Liu, Z Zheng, H Xie - MedComm, 2021 - Wiley Online Library
Mesenchymal stromal/stem cells (MSCs) have a great potential to proliferate, undergo multi‐
directional differentiation, and exert immunoregulatory effects. There is already much …

[HTML][HTML] The role of occupational and environmental exposures in the pathogenesis of idiopathic pulmonary fibrosis: a narrative literature review

SP Trethewey, GI Walters - Medicina, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterised by a
progressive and irreversible decline in lung function, which is associated with poor long …

Real-world retrospective observational study exploring the effectiveness and safety of antifibrotics in idiopathic pulmonary fibrosis

WA Wright, LE Crowley, D Parekh… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Background Pirfenidone and nintedanib are the only disease-modifying treatments available
for idiopathic pulmonary fibrosis (IPF). Our aim was to test their effectiveness and safety in …

Lead-like drugs: A perspective: Miniperspective

B Raymer, SK Bhattacharya - Journal of Medicinal Chemistry, 2018 - ACS Publications
Lead-like drugs, or drugs below molecular weight 300, are an important and sometimes
overlooked component of the current pharmacopeia and contemporary medicinal chemistry …

Mesenchymal stem cell therapy of pulmonary fibrosis: improvement with target combination

HM Chuang, TE Shih, KY Lu, SF Tsai… - Cell …, 2018 - journals.sagepub.com
Although the clinical application of new drugs has been shown to be effective in slowing
disease progression and improving the quality of life in patients with pulmonary fibrosis, the …

The impact of the Envisia genomic classifier in the diagnosis and management of patients with idiopathic pulmonary fibrosis

JA Lasky, A Case, A Unterman, M Kreuter… - Annals of the …, 2022 - atsjournals.org
Rationale: The diagnosis of idiopathic pulmonary fibrosis (IPF) remains challenging and can
result in delayed or misdiagnosis. IPF diagnosis is based on the presence of either a …

[HTML][HTML] Effects of exercise training on cardiopulmonary function and quality of life in elderly patients with pulmonary fibrosis: a meta-analysis

X Li, R Yu, P Wang, A Wang, H Huang - International Journal of …, 2021 - mdpi.com
(1) Objective: Our objective was to conduct a meta-analysis of randomized controlled trials
that have evaluated the benefits of exercise training for elderly pulmonary fibrosis (PF) …

Pirfenidone ameliorates early pulmonary fibrosis in LPS-induced acute respiratory distress syndrome by inhibiting endothelial-to-mesenchymal transition via the …

R Zhang, Y Tan, C Yong, Y Jiao, X Tang… - International …, 2022 - Elsevier
Pulmonary vascular endothelial dysfunction is a key pathogenic mechanism in acute
respiratory distress syndrome (ARDS), resulting in fibrosis in lung tissues, including in the …