[HTML][HTML] The neurobiology of irritable bowel syndrome

EA Mayer, HJ Ryu, RR Bhatt - Molecular psychiatry, 2023 - nature.com
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

Functional dyspepsia

P Enck, F Azpiroz, G Boeckxstaens… - Nature Reviews …, 2017 - nature.com
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders.
Functional dyspepsia comprises three subtypes with presumed different pathophysiology …

[HTML][HTML] Brain imaging tests for chronic pain: medical, legal and ethical issues and recommendations

KD Davis, H Flor, HT Greely, GD Iannetti… - Nature Reviews …, 2017 - nature.com
Chronic pain is the greatest source of disability globally and claims related to chronic pain
feature in many insurance and medico-legal cases. Brain imaging (for example, functional …

[HTML][HTML] Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome

JS Labus, EB Hollister, J Jacobs, K Kirbach… - Microbiome, 2017 - Springer
Background Preclinical and clinical evidence supports the concept of bidirectional brain-gut
microbiome interactions. We aimed to determine if subgroups of irritable bowel syndrome …

Towards a systems view of IBS

EA Mayer, JS Labus, K Tillisch, SW Cole… - Nature Reviews …, 2015 - nature.com
Despite an extensive body of reported information about peripheral and central mechanisms
involved in the pathophysiology of IBS symptoms, no comprehensive disease model has …

[HTML][HTML] Machine learning in pain research

J Lötsch, A Ultsch - Pain, 2018 - journals.lww.com
Pain and pain chronification are incompletely understood and unresolved medical problems
that continue to have a high prevalence. 14 It has been accepted that pain is a complex …

Role of brain imaging in disorders of brain–gut interaction: a Rome Working Team Report

EA Mayer, J Labus, Q Aziz, I Tracey, L Kilpatrick… - Gut, 2019 - gut.bmj.com
Imaging of the living human brain is a powerful tool to probe the interactions between brain,
gut and microbiome in health and in disorders of brain–gut interactions, in particular IBS …

[HTML][HTML] Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für …

P Layer, V Andresen, H Allescher… - Zeitschrift für …, 2021 - thieme-connect.com
Auch wurden ähnlich wie bei der Vorgängerleitlinie die Empfehlungen zum kindlichen
Reizdarmsyndrom und Empfehlungen zur Abgrenzung intestinaler Motilitätsstörungen …

Gastrointestinal pain

AM Drewes, AE Olesen, AD Farmer… - Nature reviews Disease …, 2020 - nature.com
Gastrointestinal (GI) pain—a form of visceral pain—is common in some disorders, such as
irritable bowel syndrome, Crohn's disease and pancreatitis. However, identifying the cause …

Etiology and treatment of pain and psychosocial issues in patients with inflammatory bowel diseases

M Regueiro, JB Greer, E Szigethy - Gastroenterology, 2017 - Elsevier
There is increasing evidence that brain− gut interactions are altered during development of
inflammatory bowel diseases (IBDs). Understanding the relationship between the …