Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …

Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

The overproduction of reactive oxygen species (ROS) and consequent oxidative stress
contribute to the pathogenesis of acute and chronic liver diseases. It is now acknowledged …

Cells are subjected to endogenous [eg, reactive oxygen species (ROS), replication stress]
and exogenous insults (eg, UV light, ionizing radiation, and certain chemicals), which can …

Ageing is a multifactorial biological process leading to a progressive decline of physiological
functions. The process of ageing includes numerous changes in the cells and the …

Interstitial lung diseases (ILDs) comprise a large and heterogeneous group of disorders of
known and unknown aetiology characterised by diffuse damage of the lung parenchyma. In …

Rationale Endoplasmic reticulum (ER) stress and mitochondrial dysfunction are important
mechanisms of atrial remodeling, predisposing to the development of atrial fibrillation (AF) in …

Glyphosate (GLY), one of the most extensively used herbicides in the world, has been
shown to inhibit testosterone synthesis in male animals. Mitochondria are crucial organelles …

Idiopathic pulmonary fibrosis (IPF) is a fibrotic interstitial lung disease in which collagen
progressively deposits in the supporting framework of the lungs. The pathological collagen …

Cardiac fibrosis (CF) is considered an ultimate common pathway of a wide variety of heart
diseases in response to diverse pathological and pathophysiological stimuli. Mitochondria …