Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2‐mediated attenuation of mitochondrial damage

N Ding, S Sun, S Zhou, Z Lv… - Cell Biochemistry and …, 2024 - Wiley Online Library
Tubulointerstitial fibrosis is an inevitable consequence of all progressive chronic kidney
disease (CKD) and contributes to a substantial health burden worldwide. Icariin, an active …

[HTML][HTML] Multifunctional biomaterial platforms for blocking the fibrosis process and promoting cellular restoring effects in myocardial fibrosis therapy

T Yue, S Xiong, D Zheng, Y Wang, P Long… - … in Bioengineering and …, 2022 - frontiersin.org
Myocardial fibrosis is the result of abnormal healing after acute and chronic myocardial
damage and is a direct cause of heart failure and cardiac insufficiency. The clinical …

Interventional‐and amputation‐stage muscle proteomes in the chronically threatened ischemic limb

TE Ryan, K Kim, ST Scali, SA Berceli… - Clinical and …, 2022 - Wiley Online Library
Background Despite improved surgical approaches for chronic limb‐threatening ischemia
(CLTI), amputation rates remain high and contributing tissue‐level factors remain unknown …

Hepatocyte nuclear factor‐1β shapes the energetic homeostasis of kidney tubule cells

A Piedrafita, S Balayssac, A Casemayou… - The FASEB …, 2021 - Wiley Online Library
Energetic metabolism controls key steps of kidney development, homeostasis, and epithelial
repair following acute kidney injury (AKI). Hepatocyte nuclear factor‐1β (HNF‐1β) is a …

[HTML][HTML] Potential role of ribonucleotide reductase enzyme in mitochondria function and woody breast condition in broiler chickens

M Shakeri, B Kong, H Zhuang, B Bowker - Animals, 2023 - mdpi.com
Simple Summary The woody breast myopathy in broiler chickens results in inferior quality
breast meat. The severity of woody breast can negatively impact consumers' acceptance …

[HTML][HTML] Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function

BM Vamesu, T Nicola, R Li, S Hazra, S Matalon… - JCI insight, 2023 - ncbi.nlm.nih.gov
Mitochondrial dysfunction at birth predicts bronchopulmonary dysplasia (BPD) in extremely
low–birth weight (ELBW) infants. Recently, nebulized thyroid hormone (TH), given as …

[HTML][HTML] Transcriptomic profiling of mare endometrium at different stages of endometrosis

A Szóstek-Mioduchowska, A Wójtowicz, A Sadowska… - Scientific Reports, 2023 - nature.com
In the current study, transcriptome profiles of mare endometrium, classified into categories I,
IIA, and IIB according to Kenney and Doig, were compared using RNA sequencing …

[HTML][HTML] Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction

L Qian, H Xu, R Yuan, W Yun, Y Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Formononetin, an isoflavone compound, has been extensively researched due to its various
biological activities, including a potent protective effect on the cardiovascular system …

[HTML][HTML] Mammary fibrosis tendency and mitochondrial adaptability in dairy cows with mastitis

X Kan, G Hu, Y Liu, P Xu, Y Huang, X Cai, W Guo, S Fu… - Metabolites, 2022 - mdpi.com
Dairy cow mammary gland fibrosis causes huge economic losses to livestock production,
however, research on dairy cow mammary gland fibrosis is in its infancy and it lacks effective …

Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression

J Chen, W Liu - Cellular Signalling, 2023 - Elsevier
Granulosa cells surround the oocytes as a component of ovarian follicles and produce sex
steroids and growth factors to support oocyte development. Mitochondria is one of the …