Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and
immune defense against pathogens, macrophages are being re-discovered as regulators of …

Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

Colorectal cancer (CRC) is a predominant malignancy worldwide, being the fourth most
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …

Colon cancer is a major human cancer accounting for about a tenth of all cancer cases thus
making it among the top three cancers in terms of incidence as well as mortality. Metastasis …

The tumor microenvironment (TME) is known to have a strong influence on tumorigenesis,
with various components being involved in tumor suppression and tumor growth. A …

Prostate cancer stem cells (PCSCs) play a critical role in prostate cancer progression and
metastasis, which remains an obstacle for successful prostate cancer treatment. Tumor …

Macrophages are a specialized class of innate immune cells with multifaceted roles in
modulation of the inflammatory response, homeostasis, and wound healing. While …

Monocytes are progenitors to macrophages and a subclass of dendritic cells (monocyte-
derived dendritic cells, MoDCs), but they also act as circulating sensors that respond to …

Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only
limited therapeutic options. CRC is not only a genetic disease with several mutations in …

CCL4, a CC chemokine, previously known as macrophage inflammatory protein (MIP)-1β,
has diverse effects on various types of immune and nonimmune cells by the virtue of its …