The mouse-adapted pathogen Chlamydia muridarum (CM) induces pathology in the mouse
genital tract but fails to do so in the gastrointestinal tract. CM is cleared from both the genital …

Chlamydia trachomatis (CT) is frequently detected in the human gastrointestinal (GI) tract
despite its leading role in sexually transmitted bacterial infections in the genital tract …

An IFNγ-susceptible mutant of Chlamydia muridarum is attenuated in pathogenicity in the
genital tract and was recently licensed as an intr acellular O ral vaccine v ector or intrOv …

To search for subunit vaccine candidates, immunogenic chlamydial antigens identified in
humans were evaluated for protection against both infection and pathology in a mouse …

As their designation implies, obligate intracellular bacteria are microbes that have
developed lifestyles so closely entwined with the cells of the hosts they infect that they can …

The obligate intracellular bacterium Chlamydia muridarum can colonize the mouse colon for
a long period, but a gamma interferon (IFN-γ)-susceptible mutant clone fails to do so …

Chlamydia spp. productively infect mucosal epithelial cells of multiple anatomical sites,
including the conjunctiva, lungs, gastrointestinal (GI) tract, and urogenital tract. We, and …

Despite the extensive efforts, there is still a lack of a licensed vaccine against Chlamydia
trachomatis in humans. The mouse genital tract infection with Chlamydia muridarum has …

Chlamydia muridarum has been used to study chlamydial pathogenesis because it induces
mice to develop hydrosalpinx, a pathology observed in C. trachomatis-infected women. We …

Following an oral inoculation, Chlamydia muridarum descends to the mouse large intestine
for long-lasting colonization. However, a mutant C. muridarum that lacks the plasmid …