Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease
The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …
metabolism, catabolism, immune responses, autophagy, survival, proliferation, and …
The long and short non-coding RNAs modulating EZH2 signaling in cancer
S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …
encoding proteins. However, they participate in developmental and biological processes …
The multidimensional role of the Wnt/β‐catenin signaling pathway in human malignancies
Several signaling pathways have been identified as important for developmental processes.
One of such important cascades is the Wnt/β‐catenin signaling pathway, which can regulate …
One of such important cascades is the Wnt/β‐catenin signaling pathway, which can regulate …
The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy
M Garg, MK Shanmugam, V Bhardwaj… - Medicinal research …, 2021 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …
Rationalizing the therapeutic potential of apigenin against cancer
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …
cancer during the past couple of decades, it remains the second largest cause of mortality in …
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
Nanotechnology has encouraged new and amended materials (metal nanoparticles) for
therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) …
therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) …
Drug repurposing for cancer therapy
Y Xia, M Sun, H Huang, WL Jin - Signal Transduction and Targeted …, 2024 - nature.com
Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …
health. Despite significant advances in surgical, radiotherapeutic and immunological …
The role of microRNA-338-3p in cancer: growth, invasion, chemoresistance, and mediators
S Mirzaei, A Zarrabi, SE Asnaf, F Hashemi, A Zabolian… - Life sciences, 2021 - Elsevier
Cancer still remains as one of the leading causes of death worldwide. Metastasis and
proliferation are abnormally increased in cancer cells that subsequently, mediate resistance …
proliferation are abnormally increased in cancer cells that subsequently, mediate resistance …
Apoptotic mechanisms of quercetin in liver cancer: recent trends and advancements
Due to rising incidence rates of liver cancer and worries about the toxicity of current
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …
Sensing the scent of death: modulation of microRNAs by curcumin in gastrointestinal cancers
M Ashrafizadeh, A Zarrabi, M Hashemipour… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …