Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities
PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
Molecular mechanism of VEGF and its role in pathological angiogenesis
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
[HTML][HTML] Mechanisms of blue light-induced eye hazard and protective measures: a review
X Ouyang, J Yang, Z Hong, Y Wu, Y Xie… - Biomedicine & …, 2020 - Elsevier
The risk of blue light exposure to human health has attracted increased research attention.
Blue light, with relatively high energy, can cause irreversible photochemical damage to eye …
Blue light, with relatively high energy, can cause irreversible photochemical damage to eye …
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy
A Arrigo, E Aragona, F Bandello - Annals of medicine, 2022 - Taylor & Francis
Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes
mellitus, representing a major cause of visual impairment in developed countries …
mellitus, representing a major cause of visual impairment in developed countries …
[HTML][HTML] Microneedles for advanced ocular drug delivery
In the field of ocular drug delivery, topical delivery remains the most common treatment
option for managing anterior segment diseases, while intraocular injections are the current …
option for managing anterior segment diseases, while intraocular injections are the current …
[HTML][HTML] Anti-VEGF-resistant retinal diseases: a review of the latest treatment options
JO Wallsh, RP Gallemore - Cells, 2021 - mdpi.com
Anti-vascular endothelial growth factor (anti-VEGF) therapy currently plays a central role in
the treatment of numerous retinal diseases, most notably exudative age-related macular …
the treatment of numerous retinal diseases, most notably exudative age-related macular …
Risk factors and biomarkers of age-related macular degeneration
NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …
Vitamin C in disease prevention and cure: an overview
The recognition of vitamin C is associated with a history of an unrelenting search for the
cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential …
cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential …
Corneal neovascularization
MP Nicholas, N Mysore - Experimental eye research, 2021 - Elsevier
The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …
Diabetic retinopathy: vascular and inflammatory disease
F Semeraro, A Cancarini, R dell'Omo… - Journal of diabetes …, 2015 - Wiley Online Library
Diabetic retinopathy (DR) is the leading cause of visual impairment in the working‐age
population of the Western world. The pathogenesis of DR is complex and several vascular …
population of the Western world. The pathogenesis of DR is complex and several vascular …