Review of applications of cyclodextrins as taste-masking excipients for pharmaceutical purposes
L Adamkiewicz, Ł Szeleszczuk - Molecules, 2023 - mdpi.com
It is widely recognized that many active pharmaceutical ingredients (APIs) have a
disagreeable taste that affects patient acceptability, particularly in children. Consequently …
disagreeable taste that affects patient acceptability, particularly in children. Consequently …
A review on cyclodextrins/estrogens inclusion complexes
SK Araj, Ł Szeleszczuk - International Journal of Molecular Sciences, 2023 - mdpi.com
This review focuses on the methods of preparation and biological, physiochemical, and
theoretical analysis of the inclusion complexes formed between estrogens and cyclodextrins …
theoretical analysis of the inclusion complexes formed between estrogens and cyclodextrins …
17-β-Estradiol—β-Cyclodextrin Complex as Solid: Synthesis, Structural and Physicochemical Characterization
AH Mazurek, Ł Szeleszczuk, K Bethanis… - Molecules, 2023 - mdpi.com
17-β-estradiol (EST) is the most potent form of naturally occurring estrogens; therefore, it has
found a wide pharmaceutical application. The major problem associated with the use of EST …
found a wide pharmaceutical application. The major problem associated with the use of EST …
Mapping the Lipid Signatures in COVID-19 Infection: Diagnostic and Therapeutic Solutions
The COVID-19 pandemic ignited research centered around the identification of robust
biomarkers and therapeutic targets. SARS-CoV-2, the virus responsible, hijacks the …
biomarkers and therapeutic targets. SARS-CoV-2, the virus responsible, hijacks the …
Effect of the Lipid Landscape on the Efficacy of Cell-Penetrating Peptides
Every cell biological textbook teaches us that the main role of the plasma membrane is to
separate cells from their neighborhood to allow for a controlled composition of the …
separate cells from their neighborhood to allow for a controlled composition of the …
[HTML][HTML] Biomedical applications of lactoferrin on the ocular surface
U Regueiro, M López-López, R Varela-Fernández… - Pharmaceutics, 2023 - mdpi.com
Lactoferrin (LF) is a first-line defense protein with a pleiotropic functional pattern that
includes anti-inflammatory, immunomodulatory, antiviral, antibacterial, and antitumoral …
includes anti-inflammatory, immunomodulatory, antiviral, antibacterial, and antitumoral …
Veklury®(remdesivir) formulations inhibit initial membrane‐coupled events of SARS‐CoV‐2 infection due to their sulfobutylether‐β‐cyclodextrin content
Background and Purpose Despite its contradictory clinical performance, remdesivir
(Veklury®) has a pivotal role in COVID‐19 therapy. Possible contributions of the vehicle …
(Veklury®) has a pivotal role in COVID‐19 therapy. Possible contributions of the vehicle …
Genetic and enzymatic characterization of Amy13E from Cellvibrio japonicus reclassifies it as a cyclodextrinase also capable of α-diglucoside degradation
GM Mascelli, CA Garcia… - Applied and Environmental …, 2024 - Am Soc Microbiol
Cyclodextrinases are carbohydrate-active enzymes involved in the linearization of circular
amylose oligosaccharides. Primarily thought to function as part of starch metabolism, there …
amylose oligosaccharides. Primarily thought to function as part of starch metabolism, there …
Unveiling the dynamic and thermodynamic interactions of hydrocortisone with β-cyclodextrin and its methylated derivatives through insights from molecular dynamics …
R Gholami, K Azizi, M Ganjali Koli - Scientific Reports, 2024 - nature.com
Cyclodextrins (CDs) can enhance the stability and bioavailability of pharmaceutical
compounds by encapsulating them within their cavities. This study utilized molecular …
compounds by encapsulating them within their cavities. This study utilized molecular …
Rationally designed β-cyclodextrin-crosslinked polyacrylamide hydrogels for cell spheroid formation and 3D tumor model construction
T Chen, Y Wen, X Song, Z Zhang, J Zhu, X Tian… - Carbohydrate …, 2024 - Elsevier
In vitro tumor models are essential for understanding tumor behavior and evaluating tumor
biological properties. Hydrogels that can mimic the tumor extracellular matrix have become …
biological properties. Hydrogels that can mimic the tumor extracellular matrix have become …