Background Cell‐free fetal DNA (cff DNA) non‐invasive prenatal testing (NIPT) is rapidly
expanding, and is being introduced at varying rates depending on country and condition …

Context Noninvasive prenatal determination of fetal sex using cell-free fetal DNA provides
an alternative to invasive techniques for some heritable disorders. In some countries this …

Objective: We developed clinical practice guidelines for congenital adrenal hyperplasia
(CAH). Participants: The Task Force included a chair, selected by The Endocrine Society …

BACKGROUND Cell-free fetal nucleic acids (cffNA) can be detected in the maternal
circulation during pregnancy, potentially offering an excellent method for early non-invasive …

OBJECTIVE: In contrast to the traditional teaching that the placenta forms an impermeable
barrier, multiple studies show that both intact fetal cells and cell-free nucleic acids circulate …

Molecular genetic testing for congenital adrenal hyperplasia (CAH) due to 21-hydroxylase
deficiency (21-OHD) is offered worldwide and is of importance for differential diagnosis …

Over the past 40 years, much effort has been spent on developing non-invasive prenatal
diagnostic methods. Since 1997, the progress of this field has been accelerated by the …

BACKGROUND: The detection of circulating nucleic acids has long been explored for the
non-invasive diagnosis of a variety of clinical conditions. In earlier studies, detection of …

Two leading European professional societies, the European Society of Human Genetics and
the European Society for Human Reproduction and Embryology, have worked together …

The goal of this study was to identify placental specific microRNAs present in maternal
plasma that differentiate between women with normal pregnancies and nonpregnant …